[Ciprofloxacin by the intravenous route in the treatment of respiratory infections].

Giornale italiano di chemioterapia Pub Date : 1989-01-01
P Mangiarotti, G Manara, L Bianchi, P D Piccioni, C Grassi
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Abstract

A clinical trial was performed to evaluate the efficacy of ciprofloxacin by iv administration in the treatment of respiratory infections. Twenty-two in-patients affected with acute lower respiratory tract infections, mainly infectious exacerbations of chronic obstructive lung disease (COLD), were treated with ciprofloxacin at the daily dosage of 400 mg iv, in two administrations. Overall clinical results were satisfactory (15 patients cured, 7 patients improved). Concerning bacteriological results, pathogen eradication was achieved in 83.3% of cases. Tolerability was good: no adverse events were observed.

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[环丙沙星经静脉途径治疗呼吸道感染]。
临床试验评价环丙沙星静脉给药治疗呼吸道感染的疗效。22例急性下呼吸道感染的住院患者,主要是慢性阻塞性肺疾病(COLD)的感染性加重,接受环丙沙星治疗,每日400mg静脉注射,分两次给药。临床结果满意(治愈15例,好转7例)。细菌学结果方面,83.3%的病例病原菌根除。耐受性良好:未观察到不良事件。
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