[IgG, IgA and IgM serum antibodies against lipopolysaccharide from Bacteroides intermedius in periodontal health and disease].

S Otake, H Kato, N Kurihara, M Yamamoto, T Kuroki, M Makimura
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Abstract

Serum antibody titers to lipopolysaccharide from Bacteroides intermedius (B. intermedius) and Bacteroides gingivalis (B. gingivalis) were measured by enzyme-linked immunosorbent assay in serum samples from subjects with healthy gingiva and patients with periodontitis. The IgG antibody titers to LPS from B. gingivalis were significantly higher in the patients group, compared with healthy controls. No such difference was found between IgG activity to LPS from B. intermedius in the healthy and the periodonitis. Likewise, no significant difference in specific IgA level was found between the group with healthy gingiva and the patients group, both in LPS from B. intermedius and B. gingivalis. The IgM antibody levels to LPS from B. intermedius and B. gingivalis were low in subjects of patients and controls.

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[牙周健康和疾病中抗中间拟杆菌脂多糖的IgG、IgA和IgM血清抗体]。
采用酶联免疫吸附法测定健康牙龈和牙周炎患者血清中对中间拟杆菌(Bacteroides intermedius)和牙龈拟杆菌(Bacteroides gingivalis)脂多糖的血清抗体滴度。与健康对照组相比,患者组对牙龈白僵菌LPS的IgG抗体滴度显著升高。健康人与牙周炎患者对中芽胞杆菌LPS的IgG活性无明显差异。同样,健康牙龈组和患者组的特异性IgA水平也没有显著差异,无论是中间芽胞杆菌还是牙龈芽胞杆菌的LPS。患者和对照组对中间白僵菌和牙龈白僵菌LPS的IgM抗体水平均较低。
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