Salmonella Hepatitis and Colitis A case report

Jose Ramon Mena Ramirez
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Abstract

Salmonella hepatitis it’s a rare yet occasionally reported complication of Salmonella infection. The pathophysiological mechanism by which the infection causes liver damage is not completely known. Its cardinal clinical characteristic is jaundice, hepatosplenomegaly, the usual transaminase range is between 300-1000 U/L and an ALT/DHL ratio < 4 is characteristic, which is useful for its distinction from viral hepatitis. Histologically, Kupffer cell hyperplasia and typhoid nodules are the characteristic findings. The prognosis is good with treatment for the infection, however a mortality of up to 20% has been reported.
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沙门氏菌肝炎和结肠炎1例报告
沙门氏菌肝炎是一种罕见但偶尔报道的沙门氏菌感染并发症。感染引起肝损伤的病理生理机制尚不完全清楚。其主要临床特征为黄疸,肝脾肿大,转氨酶正常值300-1000 U/L, ALT/DHL比值<4是特征性的,这有助于它与病毒性肝炎的区别。组织学上,库普弗细胞增生和伤寒结节是其特征性表现。对感染进行治疗后预后良好,但据报道死亡率高达20%。
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