Hepatitis screening pose a vital role among hemodialysis patients, starting from HBsAg to advanced screening using advance technique such as PCR. Occult Hepatitis B infection can be defined as those who are HBsAg negative, HBcAbs positive, and HBV DNA PCR positive. There is a gap of knowledge regarding Occult hepatitis B infection among hemodialysis patients world wild. In Palestine, there is a need to study the Hepatitis screening practices in hemodialysis unites.
肝炎筛查在血液透析患者中起着至关重要的作用，从HBsAg到采用PCR等先进技术的高级筛查。隐匿性乙型肝炎感染可定义为HBsAg阴性、hbcab阳性和HBV DNA PCR阳性。世界范围内对血液透析患者隐匿性乙型肝炎感染的认识存在空白。在巴勒斯坦，有必要研究血液透析单位的肝炎筛查做法。
{"title":"Occult HBV infection among chronic hemodialysis patients and its role in viral transmission","authors":"Qusay Abdoh","doi":"10.55920/2771-019x/1528","DOIUrl":"https://doi.org/10.55920/2771-019x/1528","url":null,"abstract":"Hepatitis screening pose a vital role among hemodialysis patients, starting from HBsAg to advanced screening using advance technique such as PCR. Occult Hepatitis B infection can be defined as those who are HBsAg negative, HBcAbs positive, and HBV DNA PCR positive. There is a gap of knowledge regarding Occult hepatitis B infection among hemodialysis patients world wild. In Palestine, there is a need to study the Hepatitis screening practices in hemodialysis unites.","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135472285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hepatitis screening pose a vital role among hemodialysis patients, starting from HBsAg to advanced screening using advance technique such as PCR. Occult Hepatitis B infection can be defined as those who are HBsAg negative, HBcAbs positive, and HBV DNA PCR positive. There is a gap of knowledge regarding Occult hepatitis B infection among hemodialysis patients world wild. In Palestine, there is a need to study the Hepatitis screening practices in hemodialysis unites.
肝炎筛查在血液透析患者中起着至关重要的作用，从HBsAg到采用PCR等先进技术的高级筛查。隐匿性乙型肝炎感染可定义为HBsAg阴性、hbcab阳性和HBV DNA PCR阳性。世界范围内对血液透析患者隐匿性乙型肝炎感染的认识存在空白。在巴勒斯坦，有必要研究血液透析单位的肝炎筛查做法。
{"title":"Occult HBV infection among chronic hemodialysis patients and its role in viral transmission","authors":"Qusay Abdoh, Mohammad Alnees","doi":"10.55920/2771-019x/1538","DOIUrl":"https://doi.org/10.55920/2771-019x/1538","url":null,"abstract":"Hepatitis screening pose a vital role among hemodialysis patients, starting from HBsAg to advanced screening using advance technique such as PCR. Occult Hepatitis B infection can be defined as those who are HBsAg negative, HBcAbs positive, and HBV DNA PCR positive. There is a gap of knowledge regarding Occult hepatitis B infection among hemodialysis patients world wild. In Palestine, there is a need to study the Hepatitis screening practices in hemodialysis unites.","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135716566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-15DOI: 10.31487/j.jcmcr.2023.01.01
Y. Uemura, Daizo Sawamura, Mitsuo Okada
A 67-year-old Japanese male patient with Helicobacter pylori infection developed severe thrombocytopenia and was diagnosed with primary immune thrombocytopenia (ITP) on December 22, 2021. He was treated with Helicobacter pylori eradication therapy, corticosteroids, and eltrombopag (ELT). The platelet count (PLT) improved rapidly; however, after ELT cancellation and corticosteroid reduction, the PLT swiftly decreased. When the corticosteroid dose was increased, the PLT rapidly increased. The corticosteroid dose was reduced immediately; however, the patient presented with subacute arterial obstruction in the right leg and ultimately underwent surgical thrombectomy and transmetatarsal amputation. After corticosteroid cancellation, the PLT again decreased swiftly. Corticosteroids and ELT were thus re-administered. The PLT showed a tendency to recover temporarily, although the drug reaction was not gradual and showed a tendency to decrease. After a repeated BM aspiration, only megakaryocytes were not detected. We determined that the pathogenesis of the severe thrombocytopenia converted from ITP to acquired amegakaryocytic thrombocytopenia (AAMT). Cases of a conversion from ITP to AAMT are extremely rare, and the mechanism underlying this conversion is not well understood. Herein, we report the first case, to the best of our knowledge, in which transmetatarsal amputation triggered the progression of ITP to AAMT.
{"title":"The Development of Acquired Amegakaryocytic Thrombocytopenia in a Patient with Idiopathic Thrombocytopenic Purpura","authors":"Y. Uemura, Daizo Sawamura, Mitsuo Okada","doi":"10.31487/j.jcmcr.2023.01.01","DOIUrl":"https://doi.org/10.31487/j.jcmcr.2023.01.01","url":null,"abstract":"A 67-year-old Japanese male patient with Helicobacter pylori infection developed severe thrombocytopenia and was diagnosed with primary immune thrombocytopenia (ITP) on December 22, 2021. He was treated with Helicobacter pylori eradication therapy, corticosteroids, and eltrombopag (ELT). The platelet count (PLT) improved rapidly; however, after ELT cancellation and corticosteroid reduction, the PLT swiftly decreased. When the corticosteroid dose was increased, the PLT rapidly increased. The corticosteroid dose was reduced immediately; however, the patient presented with subacute arterial obstruction in the right leg and ultimately underwent surgical thrombectomy and transmetatarsal amputation. After corticosteroid cancellation, the PLT again decreased swiftly. Corticosteroids and ELT were thus re-administered. The PLT showed a tendency to recover temporarily, although the drug reaction was not gradual and showed a tendency to decrease. After a repeated BM aspiration, only megakaryocytes were not detected. We determined that the pathogenesis of the severe thrombocytopenia converted from ITP to acquired amegakaryocytic thrombocytopenia (AAMT). Cases of a conversion from ITP to AAMT are extremely rare, and the mechanism underlying this conversion is not well understood. Herein, we report the first case, to the best of our knowledge, in which transmetatarsal amputation triggered the progression of ITP to AAMT.","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89791164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelo Paolo Amico, Maria Vittoria Raele, Maria Cusmai, Claudia Citarella, Marisa Megna, Maurizio Ranieri
Background: Osgood-Schlatter Disease (OSD) is one of the most common causes of anterior knee pain in children and adolescents. It is a condition with a tendency to self-resolve, and as a result, treatment is symptomatic. In the few resistant and persistent cases, surgical treatment is opted for. Familial Mediterranean Fever (FMF) is a condition due to a genetic mutation that predisposes to the risk of complicated enthesitis. Platelet-Rich Plasma (PRP) is a type of regenerative medicine based on the injection of autologous growth factors capable of regenerating injured tissues. Methods: A 14-years old patient with FMF, left-dominant OSD and a left therapy resistant patellar tendon enthesitis was recruited. Knee pain and function were assessed with Visual Analogic Scale (VAS), Western Ontario and McMaster University (WOMAC) and knee ultrasound evaluation. The patient was evaluated at T0, at the end of the PRP Treatment (T1) and two months after the end of the Treatment (T2). Moreover, a knee MRI was collected at T0 and T2. Results: At T1 and still at T2, the VAS and WOMAC scales showed a statistically significant decrease compared with the mean value at T0 and the sonographic images showed a complete resolution of the signs of disease. Conclusion: PRP has showed to be an effective and safe method in OSD treatment in a 14-years-old athlete with a concomitant patellar tendon enthesitis and FMF. The treatment enabled the 14-year-old athlete to return to competitive basketball and avoid surgery, completely resolving his symptoms.
背景:osgood - schater病(OSD)是儿童和青少年前膝关节疼痛的最常见原因之一。这是一种倾向于自我解决的状况，因此，治疗是对症的。在少数耐药和持续的病例中，选择手术治疗。家族性地中海热(FMF)是一种由基因突变引起的疾病，易患复杂的荨麻疹。富血小板血浆(PRP)是一种基于注射能够再生损伤组织的自体生长因子的再生医学。方法:选取1例14岁的FMF、左显性OSD和左治疗抵抗性髌骨肌腱炎患者。采用视觉模拟量表(VAS)、Western Ontario and McMaster University (WOMAC)和膝关节超声评估膝关节疼痛和功能。分别在T0、PRP治疗结束时(T1)和治疗结束后2个月(T2)对患者进行评估。此外，在T0和T2采集膝关节MRI。结果:在T1和T2时，VAS和WOMAC评分较T0时的平均值有统计学意义的下降，超声图像显示疾病征象完全消退。结论:PRP是一种安全有效的治疗伴有髌骨肌腱炎和FMF的14岁运动员OSD的方法。这种治疗使这位14岁的运动员得以重返赛场，避免了手术，完全解决了他的症状。
{"title":"Efficacy of platelet-rich plasma treatment in a young athlete with osgood-schlatter disease and patellar tendinopathy, suffering from familiar mediterranean fever: A case report","authors":"Angelo Paolo Amico, Maria Vittoria Raele, Maria Cusmai, Claudia Citarella, Marisa Megna, Maurizio Ranieri","doi":"10.52768/2766-7820/2583","DOIUrl":"https://doi.org/10.52768/2766-7820/2583","url":null,"abstract":"Background: Osgood-Schlatter Disease (OSD) is one of the most common causes of anterior knee pain in children and adolescents. It is a condition with a tendency to self-resolve, and as a result, treatment is symptomatic. In the few resistant and persistent cases, surgical treatment is opted for. Familial Mediterranean Fever (FMF) is a condition due to a genetic mutation that predisposes to the risk of complicated enthesitis. Platelet-Rich Plasma (PRP) is a type of regenerative medicine based on the injection of autologous growth factors capable of regenerating injured tissues. Methods: A 14-years old patient with FMF, left-dominant OSD and a left therapy resistant patellar tendon enthesitis was recruited. Knee pain and function were assessed with Visual Analogic Scale (VAS), Western Ontario and McMaster University (WOMAC) and knee ultrasound evaluation. The patient was evaluated at T0, at the end of the PRP Treatment (T1) and two months after the end of the Treatment (T2). Moreover, a knee MRI was collected at T0 and T2. Results: At T1 and still at T2, the VAS and WOMAC scales showed a statistically significant decrease compared with the mean value at T0 and the sonographic images showed a complete resolution of the signs of disease. Conclusion: PRP has showed to be an effective and safe method in OSD treatment in a 14-years-old athlete with a concomitant patellar tendon enthesitis and FMF. The treatment enabled the 14-year-old athlete to return to competitive basketball and avoid surgery, completely resolving his symptoms.","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135840907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Multiple Myeloma (MM) is the 2nd most frequently diagnosed hematologic malignancy and accounts for 10-15% of all blood cancers and 1–1.8% of all cancers. Approximately 1% plasma cell myelomas are non-secretory (NSMM) and 15% of latter are non-producers (NSNPMM) where no cytoplasmic immunoglobulin (lg) synthesis is detected
{"title":"A very rare case of light chain negative (non-producer) IgA plasma cell myeloma","authors":"Aliaa Mohamed Amer","doi":"10.52768/2766-7820/2522","DOIUrl":"https://doi.org/10.52768/2766-7820/2522","url":null,"abstract":"Multiple Myeloma (MM) is the 2nd most frequently diagnosed hematologic malignancy and accounts for 10-15% of all blood cancers and 1–1.8% of all cancers. Approximately 1% plasma cell myelomas are non-secretory (NSMM) and 15% of latter are non-producers (NSNPMM) where no cytoplasmic immunoglobulin (lg) synthesis is detected","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139353188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marchiafava-Bignami disease (MBD) is a very rare demyelinating/necrotic disorder of the corpus callosum and nearby subcortical white matter, seen mostly in chronic alcoholics. We present here the magnetic resonance imaging findings of Machiafava-Bignami disease in a 75-year-old man with a history
{"title":"Restricted diffusion in the corpus callosum: Marchiafava-Bignami disease","authors":"El Amrani Soukaina","doi":"10.52768/2766-7820/2520","DOIUrl":"https://doi.org/10.52768/2766-7820/2520","url":null,"abstract":"Marchiafava-Bignami disease (MBD) is a very rare demyelinating/necrotic disorder of the corpus callosum and nearby subcortical white matter, seen mostly in chronic alcoholics. We present here the magnetic resonance imaging findings of Machiafava-Bignami disease in a 75-year-old man with a history","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139353457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This is a retro illumination image of right eye under 10x magnification of a 12-year-old girl with bilateral microspherophakia without any systemic association. You can see a clear crystalline natural lens in globular or spherical shape with intact and stretched zonules attached to the equator of the lens all around visible after full mydriasis.
{"title":"Isolated microspherophakia","authors":"Sarath S, MD, DNB, MNAMS, FAICO","doi":"10.52768/2766-7820/2521","DOIUrl":"https://doi.org/10.52768/2766-7820/2521","url":null,"abstract":"This is a retro illumination image of right eye under 10x magnification of a 12-year-old girl with bilateral microspherophakia without any systemic association. You can see a clear crystalline natural lens in globular or spherical shape with intact and stretched zonules attached to the equator of the lens all around visible after full mydriasis.","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139353103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patients infected with different virus strains have different clinical characteristics. This study had observed the clinical indicators of COVID-19 patients infected with early virus strains, and the aim was to supplement the data of patients with early virus infection internationally
{"title":"A 29-day clinical observational study at the beginning of the epidemic: Clinical characteristics of serious COVID-19 patients infected with early virus strains","authors":"Baoqing Sun","doi":"10.52768/2766-7820/2519","DOIUrl":"https://doi.org/10.52768/2766-7820/2519","url":null,"abstract":"Patients infected with different virus strains have different clinical characteristics. This study had observed the clinical indicators of COVID-19 patients infected with early virus strains, and the aim was to supplement the data of patients with early virus infection internationally","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139354100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Familial Mediterranean Fever (FMF) is a rare hereditary autoinflammatory disease. In particular, the onset is rare in the elderly, and the symptoms are atypical, making diagnosis difficult.
{"title":"A case of familial mediterranean fever in an elderly patient experiencing recurrent fever and weigh loss","authors":"Seiji Yamashiro","doi":"10.52768/2766-7820/2518","DOIUrl":"https://doi.org/10.52768/2766-7820/2518","url":null,"abstract":"Familial Mediterranean Fever (FMF) is a rare hereditary autoinflammatory disease. In particular, the onset is rare in the elderly, and the symptoms are atypical, making diagnosis difficult.","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139354230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omentum infarction occurs when the omentum is torsioned around its long axial axis and compresses the vascular structure. Although omentum infarction is rare, it is an important pathology that should be considered in acute abdomen.
{"title":"A rare case of acute abdomen: Omental infarct","authors":"Mustafa Salis","doi":"10.52768/2766-7820/2517","DOIUrl":"https://doi.org/10.52768/2766-7820/2517","url":null,"abstract":"Omentum infarction occurs when the omentum is torsioned around its long axial axis and compresses the vascular structure. Although omentum infarction is rare, it is an important pathology that should be considered in acute abdomen.","PeriodicalId":15420,"journal":{"name":"Journal of Clinical Images and Medical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139354302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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