[Quantitative determination of immunoglobulins in serum and saliva of patients with denture stomatitis].

Abstract

A quantitative study on the immunoglobulins G, M, and A in serum and saliva was performed as well as of secretory immunoglobulin A and of the secretory component in the saliva of 35 patients with prosthetic stomatitis and 30 healthy controls without prostheses. The method of radial immune-diffusion in agar according to Mancini, modification of G. Stankova et al. (1983) was used. The study established that there was no statistically significant difference (p greater than 0.05) in the values of immunoglobulins G, M and A in the sera of the subjects from both groups. Statistically significant increase (p less than 0.001) of the values of the immunoglobulin A, secretory immunoglobulin A and secretory component was established in the saliva of the patients with prosthetic stomatitis as compared with the same values in the control group, very likely due to the local reaction of saliva to the present prosthetic constructions.