Influence of an ionic and a nonionic (sodium meglumine diatrizoate and iopromide) x-ray contrast medium of hemorrheology.

E P Strecker, M Stengel, S Witte
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引用次数: 0

Abstract

In two groups of ten patients each, an ionic and a nonionic contrast medium was injected intravenously, for digital subtraction angiography of the supra-aortic branches, to examine the influence of hemorrheologic properties. Afterward, blood samples were obtained through a central venous catheter and evaluated by a new instrument (oscillating capillary rheometer and densitometer). The viscous and elastic components of the complex blood viscosity and the hematocrit decreased after injection of ionic and nonionic contrast media. A statistically significant difference between the patient groups could not be found. The evaluated results describe an improvement of the hemorrheologic properties after contrast media injection.

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离子型和非离子型(异位聚亚胺钠和碘丙胺)x射线造影剂对血液流变学的影响。
在两组各10名患者中,静脉注射离子和非离子造影剂,对主动脉上分支进行数字减影血管造影,以检查血液流变学特性的影响。随后,通过中心静脉导管采集血液样本,并通过一种新的仪器(振荡毛细管流变仪和密度计)进行评估。注射离子型和非离子型造影剂后,复合血液黏度和红细胞压积的黏性和弹性成分均有所下降。患者组间没有统计学上的显著差异。评价结果描述了注射造影剂后血液流变学特性的改善。
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Recent developments in nonionic contrast media. Renal excretion of iopromide and iopamidol after intravenous administration in digital subtraction angiography. Pharmacokinetics of iohexol, iopamidol, iopromide, and iosimide compared with meglumine diatrizoate. Plasma level and renal excretion of iotrolan after lumbar injection in patients. Left ventricular after load as a result of levocardiography with contrast media of various osmolality.
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