{"title":"Electron microscopic study of the effects of thallium poisoning on the rat cerebellum","authors":"Mahdi Hasan, Iqbal Ashraf, V.K. Bajpai","doi":"10.1016/0379-0738(78)90108-1","DOIUrl":null,"url":null,"abstract":"<div><p>Rats were given thallium acetate (5 mg elemental thallium/kg body weight) intraperitoneally daily for 7 days. The brain was fixed by perfusion—fixation and small pieces of the cerebellum were processed for electron microscopy. Variegated mitochondrial profiles, increased incidence of electron — dense bodies and proliferation of Golgi zones were observed in the thallium — poisoned rat cerebellum. Multilamellar cytoplasmic bodies were discernible in the cerebellar cortex of the thallium-treated rats.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 1","pages":"Pages 139-146"},"PeriodicalIF":0.0000,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0379-0738(78)90108-1","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0379073878901081","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Rats were given thallium acetate (5 mg elemental thallium/kg body weight) intraperitoneally daily for 7 days. The brain was fixed by perfusion—fixation and small pieces of the cerebellum were processed for electron microscopy. Variegated mitochondrial profiles, increased incidence of electron — dense bodies and proliferation of Golgi zones were observed in the thallium — poisoned rat cerebellum. Multilamellar cytoplasmic bodies were discernible in the cerebellar cortex of the thallium-treated rats.
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