Ming-Tse Sung , Darrell D. Davidson , Rodolfo Montironi , Antonio Lopez-Beltran , Liang Cheng
{"title":"Radical prostatectomy specimen processing: A critical appraisal of sampling methods","authors":"Ming-Tse Sung , Darrell D. Davidson , Rodolfo Montironi , Antonio Lopez-Beltran , Liang Cheng","doi":"10.1016/j.cdip.2007.06.005","DOIUrl":null,"url":null,"abstract":"<div><p>Radical prostatectomy gives the most accurate and detailed information available for determining prognosis and deciding about adjuvant therapy for prostate cancer. The consistency and reproducibility of observations from these specimens requires a standardised protocol for tissue fixation, sampling, embedding and processing. Although the publication of processing protocols in recent years has led to a convergence of opinions, differences still exist in methods of handling, sampling and processing specimens. In this review article, we incorporate the processing methods for radical prostatectomy addressed in the previous reports and propose a comprehensively standardised approach to evaluate radical prostatectomy specimens.</p></div>","PeriodicalId":87954,"journal":{"name":"Current diagnostic pathology","volume":"13 6","pages":"Pages 490-498"},"PeriodicalIF":0.0000,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cdip.2007.06.005","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current diagnostic pathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0968605307000749","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
Radical prostatectomy gives the most accurate and detailed information available for determining prognosis and deciding about adjuvant therapy for prostate cancer. The consistency and reproducibility of observations from these specimens requires a standardised protocol for tissue fixation, sampling, embedding and processing. Although the publication of processing protocols in recent years has led to a convergence of opinions, differences still exist in methods of handling, sampling and processing specimens. In this review article, we incorporate the processing methods for radical prostatectomy addressed in the previous reports and propose a comprehensively standardised approach to evaluate radical prostatectomy specimens.
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