Generation and characterization of Atoh1-Cre knock-in mouse line

IF 2.4 4区 生物学 Q2 DEVELOPMENTAL BIOLOGY genesis Pub Date : 2010-06-08 DOI:10.1002/dvg.20648
Hua Yang, Xiaoling Xie, Min Deng, Xiaowei Chen, Lin Gan
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引用次数: 0

Abstract

Confocal microscope image of a neonatal Atoh1Cre/+; R26R-lacZ mouse inner ear crista. Hair cells are labeled with anti-MYO6 (red). Anti-lacZ -green- immunolabeling reveals the hair and supporting cells originated from Atoh1-lineage. For more information, see the article by Yang et al. in this issue. © 2010 Wiley-Liss, Inc.

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Atoh1-Cre敲入小鼠细胞系的建立与表征
新生儿Atoh1Cre/+的共聚焦显微镜图像R26R-lacZ小鼠内耳嵴。毛细胞用抗myo6标记(红色)。抗lacz -绿色免疫标记显示头发和支持细胞来源于atoh1谱系。有关更多信息,请参阅本期杨等人的文章。©2010 Wiley-Liss, Inc
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
genesis
genesis 生物-发育生物学
CiteScore
3.60
自引率
0.00%
发文量
40
审稿时长
6-12 weeks
期刊介绍: As of January 2000, Developmental Genetics was renamed and relaunched as genesis: The Journal of Genetics and Development, with a new scope and Editorial Board. The journal focuses on work that addresses the genetics of development and the fundamental mechanisms of embryological processes in animals and plants. With increased awareness of the interplay between genetics and evolutionary change, particularly during developmental processes, we encourage submission of manuscripts from all ecological niches. The expanded numbers of genomes for which sequencing is being completed will facilitate genetic and genomic examination of developmental issues, even if the model system does not fit the “classical genetic” mold. Therefore, we encourage submission of manuscripts from all species. Other areas of particular interest include: 1) the roles of epigenetics, microRNAs and environment on developmental processes; 2) genome-wide studies; 3) novel imaging techniques for the study of gene expression and cellular function; 4) comparative genetics and genomics and 5) animal models of human genetic and developmental disorders. genesis presents reviews, full research articles, short research letters, and state-of-the-art technology reports that promote an understanding of the function of genes and the roles they play in complex developmental processes.
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