Immunohistological characteristics of nasal polyps. A comparison with healthy mucosa and chronic sinusitis.

Rhinology. Supplement Pub Date : 1989-01-01
R Jankowski, M C Béné, A D Moneret-Vautrin, F Haas, G Faure, C Simon, M Wayoff
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引用次数: 0

Abstract

Immunohistological investigations were performed on a series of samples from 37 patients with nasal polyps, 22 with chronic sinusitis, and 15 controls with healthy nasal and sinusal mucosa. Mean numbers of plasma- and mast cells were not different in the various groups. Immunoglobulin isotypes were always predominantly IgA and IgM; IgE were scarce. Deposited immune complexes were always absent. A statistically significant difference, however, was observed in the number of eosinophils within the mucosa. Patients with nasal polyps had up to ten times more eosinophils per surface unit than patients with sinusitis or healthy mucosa.

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鼻息肉的免疫组织学特征。健康黏膜与慢性鼻窦炎的比较。
本文对37例鼻息肉患者、22例慢性鼻窦炎患者和15例正常鼻及鼻窦黏膜患者进行了免疫组织学检查。血浆细胞和肥大细胞的平均数量在各组中没有差异。免疫球蛋白亚型以IgA和IgM为主;IgE是稀缺的。沉积的免疫复合物总是不存在。然而,在粘膜内的嗜酸性粒细胞数量上观察到统计学上的显著差异。鼻息肉患者每表面单位嗜酸性粒细胞比鼻窦炎患者或健康粘膜患者多10倍。
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Position paper on olfactory dysfunction. European position paper on the anatomical terminology of the internal nose and paranasal sinuses. European Position Paper on Rhinosinusitis and Nasal Polyps 2012. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. 4-Phase-Rhinomanometry (4PR)--basics and practice 2010.
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