Bisphenol derivatives in cord blood and association between thyroid hormones and potential exposure sources.

IF 2.2 4区医学 Q3 ENVIRONMENTAL SCIENCES International Journal of Environmental Health Research Pub Date : 2024-08-01 Epub Date: 2023-11-26 DOI:10.1080/09603123.2023.2286016

Merve Buke Sahin, Murat Cagan, Anıl Yirun, Aylin Balcı Ozyurt, Selinay Basak Erdemli Kose, Irem Iyigun, Melda Celik, Ozgur Ozyuncu, Pınar Erkekoglu, Cavit Isik Yavuz

{"title":"Bisphenol derivatives in cord blood and association between thyroid hormones and potential exposure sources.","authors":"Merve Buke Sahin, Murat Cagan, Anıl Yirun, Aylin Balcı Ozyurt, Selinay Basak Erdemli Kose, Irem Iyigun, Melda Celik, Ozgur Ozyuncu, Pınar Erkekoglu, Cavit Isik Yavuz","doi":"10.1080/09603123.2023.2286016","DOIUrl":null,"url":null,"abstract":"Endocrine-disrupting environmental chemicals are a public health concern, particularly fetal exposure to Bisphenol derivatives. This study aimed to assess fetal exposure to Bisphenol derivatives (BPA, BPF, and BPS) by measuring their levels in cord blood and investigating their association with plastic material used in daily life as well as cord blood TSH and free L-thyroxine (fT4) levels. In this descriptive study, a questionnaire with a face-to-face interview was administered before birth, and cord blood samples were taken immediately after delivery. The mean levels of BPA, BPF, TSH, and fT4 were measured as 10.69 ± 2.39 ng/ml, 3.80 ± 0.58 ng/ml; 2.36 ± 0.23 µIU/ml, and 14.18 ± 0.53 pg/ml, respectively, in a total of 104 cord blood samples. All BPS levels remained below the detection limit. Linear regression analysis revealed a positive association between birth weight and cord blood BPA concentration (β = 0.26; p = 0.02). Further research on maternal exposure during the fetal and neonatal period is critical for public health.","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Environmental Health Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09603123.2023.2286016","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/11/26 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Endocrine-disrupting environmental chemicals are a public health concern, particularly fetal exposure to Bisphenol derivatives. This study aimed to assess fetal exposure to Bisphenol derivatives (BPA, BPF, and BPS) by measuring their levels in cord blood and investigating their association with plastic material used in daily life as well as cord blood TSH and free L-thyroxine (fT₄) levels. In this descriptive study, a questionnaire with a face-to-face interview was administered before birth, and cord blood samples were taken immediately after delivery. The mean levels of BPA, BPF, TSH, and fT₄ were measured as 10.69 ± 2.39 ng/ml, 3.80 ± 0.58 ng/ml; 2.36 ± 0.23 µIU/ml, and 14.18 ± 0.53 pg/ml, respectively, in a total of 104 cord blood samples. All BPS levels remained below the detection limit. Linear regression analysis revealed a positive association between birth weight and cord blood BPA concentration (β = 0.26; p = 0.02). Further research on maternal exposure during the fetal and neonatal period is critical for public health.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

脐带血中的双酚衍生物及甲状腺激素与潜在暴露源之间的关系。

干扰内分泌的环境化学物质是一个公共卫生问题，特别是胎儿接触双酚衍生物。本研究旨在通过测量脐带血中双酚衍生物(BPA, BPF和BPS)的水平，并研究它们与日常生活中使用的塑料材料以及脐带血TSH和游离l -甲状腺素(fT4)水平的关系，来评估胎儿对双酚衍生物(BPA, BPF和BPS)的暴露程度。在这项描述性研究中，在出生前进行问卷调查和面对面访谈，并在分娩后立即采集脐带血样本。BPA、BPF、TSH和fT4的平均水平分别为10.69±2.39 ng/ml、3.80±0.58 ng/ml;104份脐带血样品中，分别为2.36±0.23µIU/ml和14.18±0.53 pg/ml。所有BPS水平均低于检测限。线性回归分析显示新生儿出生体重与脐带血BPA浓度呈正相关(β = 0.26;p = 0.02)。进一步研究母体在胎儿期和新生儿期的暴露对公共卫生至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

International Journal of Environmental Health Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.70

自引率

3.10%

发文量

134

审稿时长

>12 weeks

期刊介绍： International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.