COVID-19 immune response in adults post Measles-Rubella vaccination

Vacunas (English Edition) Pub Date : 2023-10-01 DOI:10.1016/j.vacune.2023.10.008

Suwoyo Suwoyo, Erna Rahma Yani, Koekoeh Hardjito

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Abstract

Objective

This study aimed to see how measles, mumps, and rubella vaccination affected the increase in SARS-CoV-2 immunoglobulin levels in individuals who had received the second dose of the SARS-CoV-2 vaccine.

Material and method

This research is a quasi-experimental type with a pre-post test design. The population studied were adults who had received the second dose of the SARS-CoV-2 vaccine, consisting of 30 people.

Results

The results of this study were that most (60%) research subjects experienced an increase in IgM and some subjects (46.6%) experienced an increase in anti-SARS-CoV-2 IgG levels. The administration of the MR vaccination had no effect on increasing anti-SARS-CoV-2 IgG and IgM levels. This happened because the increase in IgM and IgG levels in the pre and post-tests in most research subjects was relatively low.

Conclusion

The administration of the MR vaccine to adults who had received a second dose of the SARS-CoV-2 vaccine elicited a response with low levels of IgG and IgM SARS-CoV-2.

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成人麻疹-风疹疫苗接种后的COVID-19免疫反应

目的本研究旨在了解麻疹、腮腺炎和风疹疫苗接种如何影响接受第二剂SARS-CoV-2疫苗的个体中SARS-CoV-2免疫球蛋白水平的增加。材料与方法本研究为准实验型，采用前后试验设计。研究的人群是接受了第二剂SARS-CoV-2疫苗的成年人，由30人组成。结果大多数(60%)研究对象IgM水平升高，部分(46.6%)研究对象抗sars - cov -2 IgG水平升高。MR疫苗接种对增加抗sars - cov -2 IgG和IgM水平没有影响。这是因为大多数研究对象在测试前后IgM和IgG水平的增加相对较低。结论接种过第二剂SARS-CoV-2疫苗的成人接种MR疫苗可引起低水平的SARS-CoV-2 IgG和IgM的应答。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Vacunas (English Edition)

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