Automatic detection of ischemic necrotic sites in small intestinal tissue using hyperspectral imaging and transfer learning

IF 2 3区 物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS Journal of Biophotonics Pub Date : 2023-11-29 DOI:10.1002/jbio.202300315
Lechao Zhang, Jianxia Xue, Yi Xie, Danfei Huang, Zhonghao Xie, Libin Zhu, Xiaoqing Chen, Guihua Cui, Shujat Ali, Guangzao Huang, Xiaojing Chen
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Abstract

Acquiring large amounts of hyperspectral data of small intestinal tissue with real labels in the clinic is difficult, and the data shows inter-patient variability. Building an automatic identification model using a small dataset presents a crucial challenge in obtaining a strong generalization of the model. This study aimed to explore the performance of hyperspectral imaging and transfer learning techniques in the automatic identification of normal and ischemic necrotic sites in small intestinal tissue. Hyperspectral data of small intestinal tissues were collected from eight white rabbit samples. The transfer component analysis (TCA) method was performed to transfer learning on hyperspectral data between different samples and the variability of data distribution between samples was reduced. The results showed that the TCA transfer learning method improved the accuracy of the classification model with less training data. This study provided a reliable method for single-sample modelling to detect necrotic sites in small intestinal tissue .

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利用高光谱成像和迁移学习技术自动检测小肠组织中的缺血性坏死部位。
在临床中获取具有真实标签的小肠组织的大量高光谱数据是困难的,并且数据显示出患者之间的差异。使用小数据集构建自动识别模型是获得模型强泛化的关键挑战。本研究旨在探讨高光谱成像和迁移学习技术在小肠组织正常和缺血性坏死部位自动识别中的应用。采集了8只白兔小肠组织的高光谱数据。采用传递分量分析(TCA)方法对不同样本间的高光谱数据进行迁移学习,降低了样本间数据分布的可变性。结果表明,TCA迁移学习方法在训练数据较少的情况下提高了分类模型的准确率。本研究提供了一种可靠的单样本模型检测小肠组织坏死部位的方法。这篇文章受版权保护。版权所有。
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来源期刊
Journal of Biophotonics
Journal of Biophotonics 生物-生化研究方法
CiteScore
5.70
自引率
7.10%
发文量
248
审稿时长
1 months
期刊介绍: The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.
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