The Re-emergence of Diphtheria Amidst Multiple Outbreaks in Nigeria.

Pius Omoruyi Omosigho, Okesanya Olalekan John, Olaniyi Abideen Adigun, Hakeem Kayode Hassan, Olaleke Noah Olabode, Abioye Sunday Micheal, Usman Abubakar Haruna, Amandeep Singh, Emery Manirambona
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Abstract

Diphtheria, a vaccine-preventable disease, has resurfaced in Nigeria, where many outbreaks have been reported in recent years. The outbreaks have occurred across the country, including in areas with high vaccination coverage. Corynebacterium diphtheriae, the causal agent, is a highly contagious bacteria that can cause severe respiratory and systemic symptoms and can be fatal if not treated. The reemergence of diphtheria in Nigeria is most likely due to a combination of factors, including gaps in routine immunization regimens. The outbreak is further aggravated by multiple epidemics, which have diverted resources and attention away from the emergency of other infectious diseases. Furthermore, there is a lack of awareness of diphtheria in Nigeria. With a focus on the difficulties in controlling the disease, methods of diagnosis, available treatments, and preventive measures, this study provides a thorough analysis of diphtheria, covering its historical context, clinical presentation, associated complications, and current outbreaks. It emphasizes how important vaccination, early detection, and better access to healthcare are in reducing diphtheria outbreaks. The study highlights the serious effects of diphtheria on public health, particularly in regions with scarce resources and vaccine resistance, and offers a number of suggestions to overcome these challenges and prevent further outbreaks.

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尼日利亚多次暴发白喉疫情,白喉再次出现。
白喉是一种疫苗可预防的疾病,在尼日利亚重新出现,近年来该国报告了多次疫情。疫情在全国各地发生,包括在疫苗接种覆盖率高的地区。白喉链杆菌是一种传染性很强的细菌,可引起严重的呼吸道和全身症状,如果不加以治疗,可能会致命。尼日利亚白喉的重新出现很可能是多种因素共同作用的结果,包括常规免疫方案的不足。多重流行病进一步加剧了疫情,使资源和注意力从其他传染病的紧急情况中转移出来。此外,尼日利亚对白喉缺乏认识。本研究的重点是控制该疾病的困难、诊断方法、现有治疗方法和预防措施,对白喉进行了全面分析,包括其历史背景、临床表现、相关并发症和当前爆发。它强调疫苗接种、早期发现和更好地获得卫生保健对于减少白喉疫情的重要性。该研究强调了白喉对公共卫生的严重影响,特别是在资源稀缺和疫苗耐药性的地区,并提出了一些建议,以克服这些挑战并防止进一步暴发。
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