Mind-body therapies adjuvant to chemotherapy improve quality of life and fatigue in top cancers: A systematic review and meta-analysis

IF 2.2 3区医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Complementary Therapies in Clinical Practice Pub Date : 2023-11-24 DOI:10.1016/j.ctcp.2023.101811

Lucy Ella Bailey, Mhairi Anne Morris

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Abstract

Background

Breast, lung and colorectal cancers are 3 of the top 4 most common cancers worldwide. Their treatment with chemotherapy often results in adverse effects on quality of life, fatigue and functional exercise capacity amongst patients. Mind-body therapies, including yoga, Tai chi and Qigong, are commonly used as complementary and alternative therapies in cancer. This meta-analysis evaluates the effects of yoga, Tai chi and Qigong in alleviating the adverse effects of chemotherapy.

Methods

Various databases were systematically interrogated using specific search terms, returning 1901 manuscripts. Removal of duplicates, irrelevant studies, those lacking available data and applying inclusion/exclusion criteria reduced this number to 9 manuscripts for inclusion in the final meta-analyses. Mean differences were calculated to determine pooled effect sizes using RStudio.

Results

This is the first systematic review and meta-analysis to demonstrate significant improvements in fatigue for colorectal cancer patients undergoing chemotherapy with a reduction of −1.40 (95 % CI: −2.24 to −0.56; p = 0.001) observed in mind-body therapy intervention groups.

Conclusion

Yoga, Tai chi and Qigong could all be implemented alongside adjuvant therapies to alleviate the adverse effects on colorectal cancer patient fatigue during chemotherapy treatment.

Review registration

This systematic review and meta-analysis is registered on InPlasy: registration number INPLASY202390035; doi: https://doi.org/10.37766/inplasy2023.9.0035.

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身心疗法辅助化疗可改善顶级癌症患者的生活质量和疲劳:一项系统回顾和荟萃分析

乳腺癌、肺癌和结直肠癌是世界上最常见的4种癌症中的3种。他们的化疗治疗通常会对患者的生活质量、疲劳和功能性运动能力产生不良影响。身心疗法，包括瑜伽、太极和气功，通常被用作癌症的补充和替代疗法。本荟萃分析评估了瑜伽、太极和气功在减轻化疗不良反应中的作用。方法采用特定检索词对各数据库进行系统检索，检索到论文1901篇。删除重复研究、不相关研究、缺乏可用数据的研究和应用纳入/排除标准后，最终纳入meta分析的论文数量减少到9篇。使用RStudio计算平均差异以确定合并效应大小。结果:这是首个系统回顾和荟萃分析，证明接受化疗的结直肠癌患者的疲劳显著改善，减少了- 1.40 (95% CI: - 2.24至- 0.56;P = 0.001)。结论瑜伽、太极、气功配合辅助治疗均可减轻结直肠癌患者化疗期间疲劳的不良反应。该系统评价和荟萃分析已在InPlasy注册:注册号INPLASY202390035;doi: https://doi.org/10.37766/inplasy2023.9.0035。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Complementary Therapies in Clinical Practice INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

6.30

自引率

6.70%

发文量

157

审稿时长

40 days

期刊介绍： Complementary Therapies in Clinical Practice is an internationally refereed journal published to meet the broad ranging needs of the healthcare profession in the effective and professional integration of complementary therapies within clinical practice. Complementary Therapies in Clinical Practice aims to provide rigorous peer reviewed papers addressing research, implementation of complementary therapies (CTs) in the clinical setting, legal and ethical concerns, evaluative accounts of therapy in practice, philosophical analysis of emergent social trends in CTs, excellence in clinical judgement, best practice, problem management, therapy information, policy development and management of change in order to promote safe and efficacious clinical practice. Complementary Therapies in Clinical Practice welcomes and considers accounts of reflective practice.