Concurrent, New-Onset Autoimmune Hepatitis, Celiac Disease, and Hashimoto's Thyroiditis Following COVID-19: A Case Report.

JPGN reports Pub Date : 2023-11-27 eCollection Date: 2023-11-01 DOI:10.1097/PG9.0000000000000388
Mojdeh Mostafavi, Annie Abraham, James Mueller, Wael Sayej
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Abstract

Here we describe a 13-year-old adolescent female diagnosed with concurrent autoimmune disorders including Grave disease, Celiac disease, and autoimmune hepatitis within 3 months after infection with severe acute respiratory syndrome coronavirus 2. The patient initially presented to her pediatrician with complaints of epistaxis, cessation of menses, palpitations, and weight loss. Initial evaluation showed evidence of hyperthyroidism, elevated liver enzymes, and abnormal Celiac disease serologies. Additional testing including laboratory tests, liver biopsy, and an upper endoscopy with biopsies confirmed the diagnosis of Grave disease, Celiac disease, and type 1 autoimmune hepatitis. This case highlights the importance of recognizing the risk of autoimmune disorders associated with the novel coronavirus disease 2019.

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COVID-19并发新发自身免疫性肝炎、乳糜泻和桥本甲状腺炎1例
在这里,我们描述了一位13岁的青春期女性,在感染严重急性呼吸综合征冠状病毒2后3个月内被诊断为并发自身免疫性疾病,包括严重疾病、乳糜泻和自身免疫性肝炎。患者最初以鼻出血、月经停止、心悸和体重减轻等主诉就诊于儿科医生。初步评估显示甲状腺功能亢进、肝酶升高和乳糜泻血清学异常。其他检查包括实验室检查、肝活检和上部内窥镜活检,证实了严重疾病、乳糜泻和1型自身免疫性肝炎的诊断。该病例强调了认识到与2019年新型冠状病毒病相关的自身免疫性疾病风险的重要性。
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