Judith N. Blinder, Tal Dror, Patrice L. Weiss, M. Beeri
Children who are unable to eat and drink orally require temporary or permanent enteral nutritional support via tube feeding. The objective was to describe a weaning program held at a children's rehabilitation hospital and to review the long‐term outcomes of the transition from tube nutrition to oral feeding.The parents of 82 children who took part in the ALYN intervention program from 2011 to 2022 were requested to participate in a telephone survey to learn about their child's status related to eating, education, social wellbeing, and overall health. They also provided feedback concerning their experience with the tube‐weaning program and their current reliance on support for eating‐related issues.The parents of 35 (39%) children responded. Their mean ± SD age at the time of treatment were 2.1 ± 1.76, and the mean ± SD age at the time of the survey 8.85 ± 3.96 years. Their mean current zBMI is −0.7. Overall, parents were very satisfied with the child's eating (4.7 out of 5) ± 0.7, and few reported that the child's eating affected the family mealtime routine (2.1 out of 5) ± 1.3. The children's age at weaning was significantly correlated with parental reports of concern with the child's current eating ability, with younger ages at weaning associated with lower parental concern.The data demonstrated that despite the complexity of the participants, most children succeed in achieving long‐term independent eating, good nutritional status, and social participation around mealtimes.
{"title":"Long‐term implications of a multidisciplinary tube‐weaning program: Parental perspectives","authors":"Judith N. Blinder, Tal Dror, Patrice L. Weiss, M. Beeri","doi":"10.1002/jpr3.12112","DOIUrl":"https://doi.org/10.1002/jpr3.12112","url":null,"abstract":"Children who are unable to eat and drink orally require temporary or permanent enteral nutritional support via tube feeding. The objective was to describe a weaning program held at a children's rehabilitation hospital and to review the long‐term outcomes of the transition from tube nutrition to oral feeding.The parents of 82 children who took part in the ALYN intervention program from 2011 to 2022 were requested to participate in a telephone survey to learn about their child's status related to eating, education, social wellbeing, and overall health. They also provided feedback concerning their experience with the tube‐weaning program and their current reliance on support for eating‐related issues.The parents of 35 (39%) children responded. Their mean ± SD age at the time of treatment were 2.1 ± 1.76, and the mean ± SD age at the time of the survey 8.85 ± 3.96 years. Their mean current zBMI is −0.7. Overall, parents were very satisfied with the child's eating (4.7 out of 5) ± 0.7, and few reported that the child's eating affected the family mealtime routine (2.1 out of 5) ± 1.3. The children's age at weaning was significantly correlated with parental reports of concern with the child's current eating ability, with younger ages at weaning associated with lower parental concern.The data demonstrated that despite the complexity of the participants, most children succeed in achieving long‐term independent eating, good nutritional status, and social participation around mealtimes.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"65 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Ramakrishna, Karthik Ageeru, M. Kasala, R. Krupanandan, Karnan Perumal, S. Malleeswaran, Rajanikanth V. Patcha, Joy Varghese, M. S. Reddy, B. Ramachandran, K. Sadasivam
Dengue fever (DF) is one of the common vector‐borne infections in tropical and subtropical regions worldwide. Liver involvement in DF is common and includes a wide spectrum of clinical and laboratory manifestations ranging from mild transaminitis to acute liver failure (ALF). Dengue ALF has a high mortality rate. The role of liver transplant (LT) in ALF is uncertain mainly due to co‐existing multiorgan dysfunction and the risk of re‐infection as a consequence of post‐transplant immunosuppression. Here, we report the first paediatric living donor auxiliary orthotopic LT in an adolescent boy who developed ALF due to dengue. LT for ALF associated with severe dengue may be an option for patients with isolated liver involvement not responding to standard medical management.
{"title":"The first paediatric living donor auxiliary orthotopic liver transplant for dengue acute liver failure","authors":"S. Ramakrishna, Karthik Ageeru, M. Kasala, R. Krupanandan, Karnan Perumal, S. Malleeswaran, Rajanikanth V. Patcha, Joy Varghese, M. S. Reddy, B. Ramachandran, K. Sadasivam","doi":"10.1002/jpr3.12103","DOIUrl":"https://doi.org/10.1002/jpr3.12103","url":null,"abstract":"Dengue fever (DF) is one of the common vector‐borne infections in tropical and subtropical regions worldwide. Liver involvement in DF is common and includes a wide spectrum of clinical and laboratory manifestations ranging from mild transaminitis to acute liver failure (ALF). Dengue ALF has a high mortality rate. The role of liver transplant (LT) in ALF is uncertain mainly due to co‐existing multiorgan dysfunction and the risk of re‐infection as a consequence of post‐transplant immunosuppression. Here, we report the first paediatric living donor auxiliary orthotopic LT in an adolescent boy who developed ALF due to dengue. LT for ALF associated with severe dengue may be an option for patients with isolated liver involvement not responding to standard medical management.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"129 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141656311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gastroschisis and omphalocele are common malformations of the anterior abdominal wall and can lead to significant morbidity and mortality in neonates. Despite advances in surgical care, these conditions remain challenging to manage effectively.This retrospective institutional study aimed to assess the management outcomes of neonates with anterior abdominal wall defects, specifically gastroschisis and omphalocele, in the Neonatal Intensive Care Unit (NICU) of Tikur Anbessa Specialized Hospital (TASH) (Tertiary Hospital).A retrospective review was conducted on cases of gastroschisis and omphalocele managed in the NICU of TASH from August 2018 to August 2022. Patient charts of neonates with omphalocele and gastroschisis were identified and retrieved from the NICU records. The collected data were analyzed using statistical software such as SPSS.The study included a total of 50 neonates with abdominal wall defects, consisting of 39 cases of omphalocele and 11 cases of gastroschisis. Maternal age ranged from 18 to 40 years, with a mean age of 27.6 ± 4.5 years. Associated malformations were documented in 33.3% of omphalocele cases and 18.2% of gastroschisis cases. Cardiac anomalies were the most frequently associated malformation with omphalocele. Surgical intervention was performed in 27.3% of gastroschisis cases (3 out of 11) and 41% of omphalocele cases (16 out of 39). The postsurgery mortality rate was 12.5% for both major and minor omphaloceles, with 11 deaths occurring in gastroschisis cases. Sepsis was identified as the cause of death in all neonates who did not survive.The study revealed a significantly higher mortality rate in gastroschisis cases compared to omphalocele cases. Sepsis was identified as the primary cause of death in the neonates. These findings underscore the importance of effective management strategies to prevent and manage sepsis in neonates with abdominal wall defects.
{"title":"Anterior abdominal wall defects and their management outcomes in Tikur Anbessa Specialized Hospital, neonatal intensive care unit","authors":"Abebe Habtamu, Tenagne Million","doi":"10.1002/jpr3.12110","DOIUrl":"https://doi.org/10.1002/jpr3.12110","url":null,"abstract":"Gastroschisis and omphalocele are common malformations of the anterior abdominal wall and can lead to significant morbidity and mortality in neonates. Despite advances in surgical care, these conditions remain challenging to manage effectively.This retrospective institutional study aimed to assess the management outcomes of neonates with anterior abdominal wall defects, specifically gastroschisis and omphalocele, in the Neonatal Intensive Care Unit (NICU) of Tikur Anbessa Specialized Hospital (TASH) (Tertiary Hospital).A retrospective review was conducted on cases of gastroschisis and omphalocele managed in the NICU of TASH from August 2018 to August 2022. Patient charts of neonates with omphalocele and gastroschisis were identified and retrieved from the NICU records. The collected data were analyzed using statistical software such as SPSS.The study included a total of 50 neonates with abdominal wall defects, consisting of 39 cases of omphalocele and 11 cases of gastroschisis. Maternal age ranged from 18 to 40 years, with a mean age of 27.6 ± 4.5 years. Associated malformations were documented in 33.3% of omphalocele cases and 18.2% of gastroschisis cases. Cardiac anomalies were the most frequently associated malformation with omphalocele. Surgical intervention was performed in 27.3% of gastroschisis cases (3 out of 11) and 41% of omphalocele cases (16 out of 39). The postsurgery mortality rate was 12.5% for both major and minor omphaloceles, with 11 deaths occurring in gastroschisis cases. Sepsis was identified as the cause of death in all neonates who did not survive.The study revealed a significantly higher mortality rate in gastroschisis cases compared to omphalocele cases. Sepsis was identified as the primary cause of death in the neonates. These findings underscore the importance of effective management strategies to prevent and manage sepsis in neonates with abdominal wall defects.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"72 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anthony Price, Tandis Rastegarlari, Sanober Khowaja, Kade Thompson, A. Lahiji, Michelle M. Felicella, Jing He, Annie Goodwin
Chronic intestinal pseudo‐obstruction (CIPO) is a rare, severe, and often debilitating condition that can result in significant morbidity and mortality amongst the pediatric population. Eosinophilic myenteric ganglionitis is a rare inflammatory neuropathy of the myenteric plexus with characteristic eosinophilic infiltration with and without hypogangliosis. The disorder has been previously documented as a cause of CIPO. We report the case of a 14‐year‐old male with no clear obstructive cause who, after multiple visits with a myriad of tests and workups, underwent surgical exploratory laparoscopy with the pathology returning a diagnosis of eosinophilic myenteric ganglionitis with unique lymphocytic and eosinophilic cell components.
{"title":"Eosinophilic myenteric ganglionitis: A case in a 14‐year‐old‐male","authors":"Anthony Price, Tandis Rastegarlari, Sanober Khowaja, Kade Thompson, A. Lahiji, Michelle M. Felicella, Jing He, Annie Goodwin","doi":"10.1002/jpr3.12108","DOIUrl":"https://doi.org/10.1002/jpr3.12108","url":null,"abstract":"Chronic intestinal pseudo‐obstruction (CIPO) is a rare, severe, and often debilitating condition that can result in significant morbidity and mortality amongst the pediatric population. Eosinophilic myenteric ganglionitis is a rare inflammatory neuropathy of the myenteric plexus with characteristic eosinophilic infiltration with and without hypogangliosis. The disorder has been previously documented as a cause of CIPO. We report the case of a 14‐year‐old male with no clear obstructive cause who, after multiple visits with a myriad of tests and workups, underwent surgical exploratory laparoscopy with the pathology returning a diagnosis of eosinophilic myenteric ganglionitis with unique lymphocytic and eosinophilic cell components.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"119 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naomi E. B. Tjaden, Michael Acord, Jane Minturn, Myron Allukian, P. Mamula
Intestinal webs are either congenital or acquired. There are few reported cases of either chemotherapy or nonsteroidal anti‐inflammatory medications leading to acquired intestinal webs in adults. There are limited descriptions of endoscopic interventions used for therapy of numerous duodenal webs in pediatrics. Here, we describe a 32‐month‐old patient undergoing chemotherapy who had multiple duodenal webs. The patient was diagnosed after failed gastrojejunostomy tube exchange via atypical contrast filling pattern and direct visualization with endoscopy. This patient likely has acquired duodenal webs from the combination of nonsteroidal anti‐inflammatory drug containing chemotherapy treatment and repeated tube trauma. Treatment involved serial esophagogastroduodenoscopy with a combination of endoscopic therapy including balloon dilation and incisional therapy with insulated‐tip knife and cautery scissors. The patient now tolerates G‐tube feedings.
{"title":"Thirty‐two‐month‐old with multiple duodenal webs diagnosed after failed gastrojejunostomy exchange successfully treated with combination endoscopic therapy","authors":"Naomi E. B. Tjaden, Michael Acord, Jane Minturn, Myron Allukian, P. Mamula","doi":"10.1002/jpr3.12107","DOIUrl":"https://doi.org/10.1002/jpr3.12107","url":null,"abstract":"Intestinal webs are either congenital or acquired. There are few reported cases of either chemotherapy or nonsteroidal anti‐inflammatory medications leading to acquired intestinal webs in adults. There are limited descriptions of endoscopic interventions used for therapy of numerous duodenal webs in pediatrics. Here, we describe a 32‐month‐old patient undergoing chemotherapy who had multiple duodenal webs. The patient was diagnosed after failed gastrojejunostomy tube exchange via atypical contrast filling pattern and direct visualization with endoscopy. This patient likely has acquired duodenal webs from the combination of nonsteroidal anti‐inflammatory drug containing chemotherapy treatment and repeated tube trauma. Treatment involved serial esophagogastroduodenoscopy with a combination of endoscopic therapy including balloon dilation and incisional therapy with insulated‐tip knife and cautery scissors. The patient now tolerates G‐tube feedings.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"113 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141668042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This case report details a novel case of Wernicke encephalopathy (WE) in a 16‐year‐old boy with obesity and chronic cannabis use. Despite the absence of alcohol use disorder, this adolescent developed classic symptoms of WE, challenging the conventional diagnostic framework. Clinical suspicion for WE was supported by typical magnetic resonance imaging findings, low thiamine levels and rapid clinical improvement postintravenous thiamine supplementation. This case underscores the need for heightened clinical vigilance for WE in patients who present with neurologic symptoms who endorse history of persistent emesis, regardless of their history of alcohol use. It also supports the preemptive administration of thiamine in those at risk of deficiency.
本病例报告详细介绍了一例新型韦尼克脑病（Wernicke encephalopathy，WE）病例，患者是一名 16 岁男孩，患有肥胖症并长期吸食大麻。尽管没有酒精使用障碍，这名青少年却出现了典型的韦尼克脑病症状，这对传统诊断框架提出了挑战。典型的磁共振成像结果、低硫胺素水平以及静脉补充硫胺素后临床症状的迅速改善都支持了临床上对 WE 的怀疑。本病例强调，对于出现神经系统症状并有持续性呕吐病史的患者，无论其是否有饮酒史，临床上都需要提高对 WE 的警惕。该病例还支持对有可能缺乏硫胺素的患者进行先期硫胺素补充。
{"title":"Wernicke encephalopathy in a pediatric patient with cannabinoid hyperemesis: A novel case report","authors":"Melissa Munroe, Zalan Shah, Aniruddh Setya","doi":"10.1002/jpr3.12109","DOIUrl":"https://doi.org/10.1002/jpr3.12109","url":null,"abstract":"This case report details a novel case of Wernicke encephalopathy (WE) in a 16‐year‐old boy with obesity and chronic cannabis use. Despite the absence of alcohol use disorder, this adolescent developed classic symptoms of WE, challenging the conventional diagnostic framework. Clinical suspicion for WE was supported by typical magnetic resonance imaging findings, low thiamine levels and rapid clinical improvement postintravenous thiamine supplementation. This case underscores the need for heightened clinical vigilance for WE in patients who present with neurologic symptoms who endorse history of persistent emesis, regardless of their history of alcohol use. It also supports the preemptive administration of thiamine in those at risk of deficiency.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":" 405","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Beeri, Tal Dror, Patrice L. Weiss, Judith N. Blinder
Children maintain growth and development by ingesting adequate calories and nutrients, typically achieved via oral intake of food and liquids. When unable to eat and drink orally, they need temporary or permanent enteral nutritional support via nasogastric, nasoduodenal, gastrostomy, or jejunostomy tubes. The objectives of this retrospective study are to describe lessons learned from operating a weaning program at ALYN Hospital for over a decade, the characteristics of the patient population (gender, age, medical condition, and type of tube feeding and hospitalization), and which of these characteristics correlate with successful weaning.Data were obtained from the hospital's secure database of 82 infants and toddlers, 37 boys (45.4%) and 45 girls (54.9%) aged 3 months to 10.8 years who took part in a tube feeding intervention from 2011 to 2020. Descriptive and correlational analyses were performed to characterize the participants and their responses to the program.Fifty‐one children (62.2%) were less than 2 years, 26 children (31.7%) were 2–4.11 years, and only 5 children were aged 5 years (6.1%) and older. Fifty‐six children were successfully weaned from tube feeding, 9 children were eventually successful, but the process took longer than anticipated, 11 children were partially weaned and 6 were not successfully weaned.These results are discussed within the context of a successful weaning program related to participant characteristics (medical condition, age, gender, and weight), and subsequent recommendations are offered related to the intervention setting, duration, and intensity; redefining success in weaning and the need for long‐term follow‐up.
{"title":"A multidisciplinary program to wean infants and toddlers from long‐term tube feeding: Lessons learned from a retrospective study","authors":"M. Beeri, Tal Dror, Patrice L. Weiss, Judith N. Blinder","doi":"10.1002/jpr3.12104","DOIUrl":"https://doi.org/10.1002/jpr3.12104","url":null,"abstract":"Children maintain growth and development by ingesting adequate calories and nutrients, typically achieved via oral intake of food and liquids. When unable to eat and drink orally, they need temporary or permanent enteral nutritional support via nasogastric, nasoduodenal, gastrostomy, or jejunostomy tubes. The objectives of this retrospective study are to describe lessons learned from operating a weaning program at ALYN Hospital for over a decade, the characteristics of the patient population (gender, age, medical condition, and type of tube feeding and hospitalization), and which of these characteristics correlate with successful weaning.Data were obtained from the hospital's secure database of 82 infants and toddlers, 37 boys (45.4%) and 45 girls (54.9%) aged 3 months to 10.8 years who took part in a tube feeding intervention from 2011 to 2020. Descriptive and correlational analyses were performed to characterize the participants and their responses to the program.Fifty‐one children (62.2%) were less than 2 years, 26 children (31.7%) were 2–4.11 years, and only 5 children were aged 5 years (6.1%) and older. Fifty‐six children were successfully weaned from tube feeding, 9 children were eventually successful, but the process took longer than anticipated, 11 children were partially weaned and 6 were not successfully weaned.These results are discussed within the context of a successful weaning program related to participant characteristics (medical condition, age, gender, and weight), and subsequent recommendations are offered related to the intervention setting, duration, and intensity; redefining success in weaning and the need for long‐term follow‐up.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Al Dogom, Jerapas Thongpiya, Marawan Elmassry, Mark Feist, Meenu Sharma, George Rateb
Esophageal granular cell tumors (GCTs) are rare mesenchymal neoplasms that originate from the Schwann cells of the neural sheath in the esophageal wall. Esophageal GCTs represent approximately 2% of all GCTs. Most cases of esophageal GCT occur in adults with few cases reported in pediatric patients. Although typically benign, these tumors can occasionally exhibit malignant behavior, necessitating timely and appropriate intervention. Traditionally, surgical resection was considered for treatment, nonetheless, considering the invasive nature of such interventions, endoscopic approaches have been developed for diagnosis and treatment. Endoscopic approaches have been shown to lead to serious complications at times, such as incomplete resection or perforation. Here, we present a successful application of endoscopic submucosal dissection in the treatment of an adolescent female patient with esophageal GCT which was discovered during her prior esophagogastroduodenoscopy for vomiting.
{"title":"Successful endoscopic submucosal dissection of an esophageal granular cell tumor in a pediatric patient: A case report and a therapeutic insight","authors":"Sara Al Dogom, Jerapas Thongpiya, Marawan Elmassry, Mark Feist, Meenu Sharma, George Rateb","doi":"10.1002/jpr3.12106","DOIUrl":"https://doi.org/10.1002/jpr3.12106","url":null,"abstract":"Esophageal granular cell tumors (GCTs) are rare mesenchymal neoplasms that originate from the Schwann cells of the neural sheath in the esophageal wall. Esophageal GCTs represent approximately 2% of all GCTs. Most cases of esophageal GCT occur in adults with few cases reported in pediatric patients. Although typically benign, these tumors can occasionally exhibit malignant behavior, necessitating timely and appropriate intervention. Traditionally, surgical resection was considered for treatment, nonetheless, considering the invasive nature of such interventions, endoscopic approaches have been developed for diagnosis and treatment. Endoscopic approaches have been shown to lead to serious complications at times, such as incomplete resection or perforation. Here, we present a successful application of endoscopic submucosal dissection in the treatment of an adolescent female patient with esophageal GCT which was discovered during her prior esophagogastroduodenoscopy for vomiting.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Wen Wei Ho, Lynette Suk‐hui Goh, Lay Queen Ng, Charanya Rajan, V. Logarajah, F. K. Chiou
Haemostatic spray (HS; Hemospray) is a powder agent for endoscopic haemostasis in patients with acute upper gastrointestinal bleeding (UGIB). It has been shown to be effective and easy to administer. However, published data on efficacy and safety in children remain scarce. Our aim was to describe our experience with the use of HS in the management of UGIB.A retrospective review was conducted of patients aged 0–18 receiving HS for endoscopic haemostasis from January 2017 to December 2021. Information was obtained on demographics, clinical presentation and comorbidities. Outcomes were successful initial haemostasis and rates of re‐bleeding.A total of 25 applications of HS occurred in 23 patients. The median patient age was 8 years (range: 4 months to 16 years). HS was used in 17/25 (68%) applications as monotherapy. Other treatments employed were clip application and adrenaline injection. One hundred per cent initial haemostasis was achieved with three (13.0%) patients who experienced re‐bleeding. All patients tolerated HS applications with no adverse events.Our finding supports the use of HS in the management of UGIB in children. HS, either as monotherapy or in combination with other conventional therapy, could potentially be the treatment of choice in children with UGIB with its excellent feasibility and good safety profile.
{"title":"Haemostatic spray in the management of acute nonvariceal upper gastrointestinal bleeding in children: A single‐centre experience in Singapore","authors":"Christopher Wen Wei Ho, Lynette Suk‐hui Goh, Lay Queen Ng, Charanya Rajan, V. Logarajah, F. K. Chiou","doi":"10.1002/jpr3.12105","DOIUrl":"https://doi.org/10.1002/jpr3.12105","url":null,"abstract":"Haemostatic spray (HS; Hemospray) is a powder agent for endoscopic haemostasis in patients with acute upper gastrointestinal bleeding (UGIB). It has been shown to be effective and easy to administer. However, published data on efficacy and safety in children remain scarce. Our aim was to describe our experience with the use of HS in the management of UGIB.A retrospective review was conducted of patients aged 0–18 receiving HS for endoscopic haemostasis from January 2017 to December 2021. Information was obtained on demographics, clinical presentation and comorbidities. Outcomes were successful initial haemostasis and rates of re‐bleeding.A total of 25 applications of HS occurred in 23 patients. The median patient age was 8 years (range: 4 months to 16 years). HS was used in 17/25 (68%) applications as monotherapy. Other treatments employed were clip application and adrenaline injection. One hundred per cent initial haemostasis was achieved with three (13.0%) patients who experienced re‐bleeding. All patients tolerated HS applications with no adverse events.Our finding supports the use of HS in the management of UGIB in children. HS, either as monotherapy or in combination with other conventional therapy, could potentially be the treatment of choice in children with UGIB with its excellent feasibility and good safety profile.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"8 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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