Research progress on Prunella vulgaris and its monomers in protecting against ulcerative colitis

Fu Jinyin , Yuan Yue , Li Xiaojia , Lin Peng , Wang Shuibin , Xiao Mingzhu
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Abstract

Prunella vulgaris is a traditional Chinese herbal medicine with many pharmacological effects, among which the anti-inflammatory effect is more significant. It is widely reported that Prunella vulgaris has anti-inflammatory, antioxidant, immune regulation, intestinal flora regulation and intestinal barrier protection effects on ulcerative colitis (UC). This paper collected relevant reports to further summarize the mechanisms and effective parts of Prunella vulgaris and its monomers in the treatment of UC and provided theoretical basis and reference for the application of Prunella vulgaris in UC.

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夏枯草及其单体抗溃疡性结肠炎的研究进展
夏枯草是一种具有多种药理作用的传统中草药,其中抗炎作用更为显著。文献广泛报道夏枯草对溃疡性结肠炎(UC)具有抗炎、抗氧化、免疫调节、肠道菌群调节和肠道屏障保护作用。本文收集相关报道,进一步总结夏枯草及其单体治疗UC的作用机理和有效部位,为夏枯草在UC中的应用提供理论依据和参考。
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