Modulation of inflammatory response and pain by mind-body therapies as meditation

Brain Behavior and Immunity Integrative Pub Date : 2023-11-30 DOI:10.1016/j.bbii.2023.100036

Juan J. Moreno

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Abstract

In the last decade, meditation practice has been extended and is becoming increasingly popular whereas, the research to understand the effects of meditation on the health is growing. The aim of this review/commentary is explored how meditation can modulate stress and stress effects on brain-endocrine-immune axis to understand the main genomic/metabolomic elements and mechanisms involved in the effects of meditation on the inflammatory process including the modulation of the pain. World Health Organization considers that by 2030 depression and stress-related disorders will be the most widespread health problems, closely followed by inflammatory processes such as autoimmune diseases, allergy and diseases associated to chronic low-grade inflammation. Thus, this review contributes to the evidence-based integration of meditation practices into clinical care for reducing the burden of chronic diseases and lowering the overall cost of healthcare; and analysing the limitations, safety, and possible contraindications.

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通过冥想等身心疗法调节炎症反应和疼痛

在过去的十年中，冥想练习已经扩展并变得越来越受欢迎，而了解冥想对健康影响的研究也越来越多。这篇综述/评论的目的是探讨冥想如何调节压力和压力对脑内分泌-免疫轴的影响，以了解冥想对炎症过程(包括疼痛调节)影响的主要基因组/代谢组学因素和机制。世界卫生组织认为，到2030年，抑郁症和与压力有关的疾病将成为最普遍的健康问题，紧随其后的是自身免疫性疾病、过敏和与慢性低度炎症相关的疾病等炎症过程。因此，本综述有助于以证据为基础的冥想实践整合到临床护理中，以减轻慢性病的负担和降低医疗保健的总体成本;并分析其局限性、安全性和可能的禁忌症。

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Brain Behavior and Immunity Integrative

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