Technical note: Excel spreadsheet calculation of the Henssge equation as an aid to estimating postmortem interval

IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Journal of forensic and legal medicine Pub Date : 2023-12-06 DOI:10.1016/j.jflm.2023.102634
Masaomi Otatsume , Norihiro Shinkawa , Myu Tachibana , Hisanaga Kuroki , Ayako Ro , Ai Sonoda , Eiji Kakizaki , Nobuhiro Yukawa
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Abstract

In forensic cases for which the time of death is unknown, several methods are used to estimate the postmortem interval. The quotient (Q) defined as the difference between the rectal and ambient temperature (Tr − Ta) divided by the initial difference (T0 − Ta) represents the progress of postmortem cooling: Q = (Tr − Ta)/(T0 − Ta), (1 ≥ Q ≥ 0). Henssge was able to show that with the body weight and its empirical corrective factor, Q can be reasonably predicted as a double exponential decay function of time (Qp(t)). On the other hand, actual Q is determined as Qd by measuring Tr and Ta under an assumption of T0 = 37.2 °C. Then, the t value at which Qp(t) is equal to Qd (Qd=Qp(t)) would be a good estimate of the postmortem interval (the Henssge equation). Since the equation cannot be solved analytically, it has been solved using a pair of nomograms devised by Henssge. With greater access to computers and spreadsheet software, computational methods based on the input of actual parameters of the case can be more easily utilized. In this technical note, we describe two types of Excel spreadsheets to solve the equation numerically. In one type, a fairly accurate solution was obtained by iteration using an add-in program Solver. In the other type (forward calculation), a series of Qp(t) was generated at a time interval of 0.05 h and the t value at which Qp(t) was nearest to Qd was selected as an approximate solution using a built-in function, XLOOKUP. Alternatively, a series of absolute values of the difference between Qd and Qp(t) (|Dq(t)| = |Qd − Qp(t)|) was generated with time interval 0.1 h and the t value that produces the minimum |Dq(t)| was selected. These Excel spreadsheets are available as Supplementary Files.

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技术说明:亨斯格方程的Excel电子表格计算,以帮助估计死后时间间隔
在死亡时间不明的法医案件中,使用几种方法来估计死后间隔。商(Q)定义为直肠之间的差异和环境温度(Tr − Ta)除以初始差异(T0 − Ta)代表了后期冷却的进步:Q = (Tr − Ta) / (T0 − Ta),(1 ≥ 问 ≥ 0)。Henssge能够证明,结合体重及其经验校正因子,Q可以合理地预测为时间的双指数衰减函数(Qp(t))。另一方面,在假设T0 = 37.2 °C下,通过测量Tr和Ta来确定实际Q为Qd。那么,Qp(t)等于Qd (Qd=Qp(t))时的t值将是对死后时间间隔的一个很好的估计(亨斯格方程)。由于这个方程不能解析解,所以用Henssge设计的一对诺图来解。随着更多地使用计算机和电子表格软件,基于实际参数输入的计算方法可以更容易地利用。在本技术说明中,我们描述了两种类型的Excel电子表格来数值求解方程。在其中一种类型中,使用外接程序Solver通过迭代得到了相当精确的解。在另一种类型(前向计算)中,以0.05 h为时间间隔生成一系列Qp(t),并使用内置函数XLOOKUP选择Qp(t)最接近Qd的t值作为近似解。或者生成一系列Qd与Qp(t)之差的绝对值(|Dq(t)| = |Qd − Qp(t)|),时间间隔为0.1 h,选择产生最小值的t值|Dq(t)|。这些Excel电子表格作为补充文件提供。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.70
自引率
6.70%
发文量
106
审稿时长
57 days
期刊介绍: The Journal of Forensic and Legal Medicine publishes topical articles on aspects of forensic and legal medicine. Specifically the Journal supports research that explores the medical principles of care and forensic assessment of individuals, whether adult or child, in contact with the judicial system. It is a fully peer-review hybrid journal with a broad international perspective. The Journal accepts submissions of original research, review articles, and pertinent case studies, editorials, and commentaries in relevant areas of Forensic and Legal Medicine, Context of Practice, and Education and Training. The Journal adheres to strict publication ethical guidelines, and actively supports a culture of inclusive and representative publication.
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