Effects of Buprenorphine, Methadone and Substance-Use on COVID-19 Morbidity and Mortality

Nicholaus Christian, Xin Zhou, Rajiv Radhakrishnan
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Abstract

Objectives Substance use disorder has been associated with increased morbidity in COVID-19 infection. However, less is known about the impact of active substance use and medications for opioid use disorder (MOUD) on COVID-19 outcomes. We conducted a retrospective cohort study to evaluate the impact of substance use, namely cannabis, cocaine, alcohol, sedative and opioid use as well as buprenorphine or methadone = on COVID-19 morbidity and mortality.
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丁丙诺啡、美沙酮及药物使用对COVID-19发病率和死亡率的影响
物质使用障碍与COVID-19感染的发病率增加有关。然而,人们对活性物质使用和阿片类药物使用障碍(mod)药物对COVID-19结局的影响知之甚少。我们进行了一项回顾性队列研究,以评估物质使用(即大麻、可卡因、酒精、镇静剂和阿片类药物使用以及丁丙诺啡或美沙酮)对COVID-19发病率和死亡率的影响。
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