Mass Spectrometry-Based Proteomic Profiling of Sonicate Fluid Differentiates Staphylococcus aureus Periprosthetic Joint Infection from Non-Infectious Failure: A pilot study
Cody R. Fisher, Kiran K. Mangalaparthi, Kerryl E. Greenwood-Quaintance, Matthew P. Abdel, Akhilesh Pandey, Robin Patel
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Abstract
Purpose This study aims to use proteomic profiling of sonicate fluid samples to compare host response during Staphylococcus aureus-associated periprosthetic joint infection (PJI) and non-infected arthroplasty failure (NIAF) and investigate novel biomarkers to increase diagnostic accuracy.
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