Janna N. Vrijsen, Hanah Windbergs, Eni S. Becker, Norbert Scherbaum, Bernhard W. Müller, Indira Tendolkar
{"title":"A Randomized Controlled Pilot Study Exploring the Additive Clinical Effect of Cognitive Bias Modification-Memory in Depressed Inpatients","authors":"Janna N. Vrijsen, Hanah Windbergs, Eni S. Becker, Norbert Scherbaum, Bernhard W. Müller, Indira Tendolkar","doi":"10.1007/s10608-023-10452-y","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Depression often leads to clinical admission. Stimulating positive memory bias through repeated retrieval can counteract a ruminative depressotypic processing style. Cognitive Bias Modification (CBM)-Memory is a psychological intervention, which was evaluated as possible adjunct treatment for depressed inpatients.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>A randomized controlled pilot study with a one-week follow-up was implemented to compare the effect of a four-session positive CBM-Memory intervention to a neutral CBM-Memory version. Training-congruent retrieval (as manipulation check), and transfer to rumination (as mechanistic target) and depressive symptoms (self-rated and clinician-rated; indication of clinical relevance) were assessed.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>In the intention-to-treat sample (N = 81, <i>M</i><sub><i>age</i></sub>=35.6/<i>SD</i> = 11.9, 60% female), condition-congruent memory retrieval of previously presented target words was found after the training and at follow-up (large effect-sizes). Positive CBM-Memory intervention resulted in sustained recall bias and largest rumination reduction with a small-medium effect size. Additionally, the conditions did not differ significantly on the reduction in depressive symptoms.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Positive CBM-Memory intervention yielded positive recall bias, which was still present one week later. Additionally, the positive condition did yield more decrease in trait (but not state) rumination, providing some support for rumination as mechanistic target of positive CBM-Memory. However, there was no evidence for transfer of the training effect to depressive symptoms, indicating no superiority on clinical recovery of the positive over the neutral condition. Future research should examine a higher dosage, integration of CBM in the treatment provision, and its long-term effects in a well-powered trial.</p>","PeriodicalId":48316,"journal":{"name":"Cognitive Therapy and Research","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cognitive Therapy and Research","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1007/s10608-023-10452-y","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Depression often leads to clinical admission. Stimulating positive memory bias through repeated retrieval can counteract a ruminative depressotypic processing style. Cognitive Bias Modification (CBM)-Memory is a psychological intervention, which was evaluated as possible adjunct treatment for depressed inpatients.
Methods
A randomized controlled pilot study with a one-week follow-up was implemented to compare the effect of a four-session positive CBM-Memory intervention to a neutral CBM-Memory version. Training-congruent retrieval (as manipulation check), and transfer to rumination (as mechanistic target) and depressive symptoms (self-rated and clinician-rated; indication of clinical relevance) were assessed.
Results
In the intention-to-treat sample (N = 81, Mage=35.6/SD = 11.9, 60% female), condition-congruent memory retrieval of previously presented target words was found after the training and at follow-up (large effect-sizes). Positive CBM-Memory intervention resulted in sustained recall bias and largest rumination reduction with a small-medium effect size. Additionally, the conditions did not differ significantly on the reduction in depressive symptoms.
Conclusions
Positive CBM-Memory intervention yielded positive recall bias, which was still present one week later. Additionally, the positive condition did yield more decrease in trait (but not state) rumination, providing some support for rumination as mechanistic target of positive CBM-Memory. However, there was no evidence for transfer of the training effect to depressive symptoms, indicating no superiority on clinical recovery of the positive over the neutral condition. Future research should examine a higher dosage, integration of CBM in the treatment provision, and its long-term effects in a well-powered trial.
期刊介绍:
Cognitive Therapy and Research (COTR) focuses on the investigation of cognitive processes in human adaptation and adjustment and cognitive behavioral therapy (CBT). It is an interdisciplinary journal welcoming submissions from diverse areas of psychology, including cognitive, clinical, developmental, experimental, personality, social, learning, affective neuroscience, emotion research, therapy mechanism, and pharmacotherapy.