{"title":"Carbon Nanotubes: A Targeted Drug Delivery against Cancer Cell","authors":"Prashant Kumar, Surya Nath Pandey, Farman Ahmad, Anurag Verma, Himanshu Sharma, Sumel Ashique, Subhra Prakash Bhattacharyya, Shubneesh Kumar, Shubneesh Kumar, Neeraj Mishra, Ashish Garg","doi":"10.2174/0115734137271865231105070727","DOIUrl":null,"url":null,"abstract":": Drug delivery in human subjects has been the most difficult task since the ancient time of the medical sector. An ideal drug delivery system is, one that minimizes the adverse effects and maximizes the desired effects of the drug candidate. Various drug delivery systems have been developed that may have some kind of advantages and disadvantages, among them targeted drug delivery system is more preferable and convenient which may employ various nanoparticles or other materials for the drug delivery at the specified site of action. In this, the authors elaborately and comprehensively explained the role of recent carbon nanotubes (CNTs) in targeted drug delivery systems (specifically for targeting cancerous cells). The authors also described the methods of preparation of CNTs, characterization techniques for CNTs, cellular penetration of, CNTs, and the associated toxicities with CNTs. Carbon nanotubes are preferable to other nanoparticles because they are more electrically, mechanically, and organically stable than others, they can carry more amount of drug in comparison to other nanoparticles and their functionalization property makes them more attractive as a carrier molecule for targeting any root cause of the disease.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Nanoscience","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.2174/0115734137271865231105070727","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
: Drug delivery in human subjects has been the most difficult task since the ancient time of the medical sector. An ideal drug delivery system is, one that minimizes the adverse effects and maximizes the desired effects of the drug candidate. Various drug delivery systems have been developed that may have some kind of advantages and disadvantages, among them targeted drug delivery system is more preferable and convenient which may employ various nanoparticles or other materials for the drug delivery at the specified site of action. In this, the authors elaborately and comprehensively explained the role of recent carbon nanotubes (CNTs) in targeted drug delivery systems (specifically for targeting cancerous cells). The authors also described the methods of preparation of CNTs, characterization techniques for CNTs, cellular penetration of, CNTs, and the associated toxicities with CNTs. Carbon nanotubes are preferable to other nanoparticles because they are more electrically, mechanically, and organically stable than others, they can carry more amount of drug in comparison to other nanoparticles and their functionalization property makes them more attractive as a carrier molecule for targeting any root cause of the disease.
期刊介绍:
Current Nanoscience publishes (a) Authoritative/Mini Reviews, and (b) Original Research and Highlights written by experts covering the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano-structures, nano-bubbles, nano-droplets and nanofluids. Applications of nanoscience in physics, material science, chemistry, synthesis, environmental science, electronics, biomedical nanotechnology, biomedical engineering, biotechnology, medicine and pharmaceuticals are also covered. The journal is essential to all researches involved in nanoscience and its applied and fundamental areas of science, chemistry, physics, material science, engineering and medicine.
Current Nanoscience also welcomes submissions on the following topics of Nanoscience and Nanotechnology:
Nanoelectronics and photonics
Advanced Nanomaterials
Nanofabrication and measurement
Nanobiotechnology and nanomedicine
Nanotechnology for energy
Sensors and actuator
Computational nanoscience and technology.