Pub Date : 2024-07-23DOI: 10.2174/0115734137293979240709113456
Shangdian Wang, Zhiwei Zhou, Songhong Yang, Zilu Guo, Ting Le, Jun Wu, Zhiyu Guan, Wenjun Liu, Wenting Wu
Essential Oil (EO) is widely usedin medicine because of its antioxidant, antiinflammatory, antibacterial, antimicrobial, and antiviral properties. However, the hydrophobicity, volatility, instability, and potential toxicity of EO make it difficult to achieve efficient delivery in vivo, which limits its application. In recent years, nano drug delivery systems have been gradually applied to encapsulate EO to improve their physical and chemical properties. In order to further improve the delivery efficiency of EOs, this review summarized the commonly used nano delivery systems for EOs, analyzed their preparation principles, and listed the factors affecting the delivery efficiency of essential oils. Moreover, the challenges faced by the EO delivery system are sorted out, and the corresponding solutions are proposed, with the hope of indicating the development direction for expanding the application of the nano drug delivery system in EO.
{"title":"Research Progress in Essential Oil Nanodelivery Systems","authors":"Shangdian Wang, Zhiwei Zhou, Songhong Yang, Zilu Guo, Ting Le, Jun Wu, Zhiyu Guan, Wenjun Liu, Wenting Wu","doi":"10.2174/0115734137293979240709113456","DOIUrl":"https://doi.org/10.2174/0115734137293979240709113456","url":null,"abstract":"Essential Oil (EO) is widely usedin medicine because of its antioxidant, antiinflammatory, antibacterial, antimicrobial, and antiviral properties. However, the hydrophobicity, volatility, instability, and potential toxicity of EO make it difficult to achieve efficient delivery in vivo, which limits its application. In recent years, nano drug delivery systems have been gradually applied to encapsulate EO to improve their physical and chemical properties. In order to further improve the delivery efficiency of EOs, this review summarized the commonly used nano delivery systems for EOs, analyzed their preparation principles, and listed the factors affecting the delivery efficiency of essential oils. Moreover, the challenges faced by the EO delivery system are sorted out, and the corresponding solutions are proposed, with the hope of indicating the development direction for expanding the application of the nano drug delivery system in EO.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141779973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-18DOI: 10.2174/0115734137311390240630120055
Ghanshyam Parmar, Jay Mukesh Chudasama, Chintan Aundhia
: The pharmaceutical sciences are gradually shielding mankind from a plethora of deadly but as-of-yet-undiscovered ailments. Many diseases, some of which can be fatal, have their initial line of defence on the skin. A significant challenge for scientists is the development of appropriate pharmacological formulations for transdermal drug administration. Low side effect risk reduces first-pass impact, and good patient compliance makes transdermal distribution superior to oral delivery. This is why transdermal medication delivery is so important. Thanks to advancements in pharmaceutical delivery systems, the skin can now absorb medications more effectively. Researchers from different parts of the globe have investigated many different kinds of medications as possible transdermal delivery routes using electrospinning nanofibres. The skin can more easily absorb therapeutic compounds thanks to the nanofibres' ability to concentrate them. It is possible to load hydrophilic and lipophilic medications onto polymeric nanofibres. Another option is the transdermal distribution of biopolymer nanofibres. Over long periods of time, they control the release of medicinal substances. Nanofibres and nanoparticles allow for the controlled release of both hydrophobic and hydrophilic drugs. Transdermal and topical medication delivery using polymeric electrospinning nanofibres laden with nanoparticles and medicines is the subject of this research review. After that, we'll look at some practical instances of engineers using electrospinning fibres to control the release of drugs in reaction to environmental and internal factors. Afterwards, we will quickly go over the latest developments in tissue engineering, hard tissue engineering [which includes repairing musculoskeletal systems, bones, and cartilage], and cancer therapy that uses electrospin nanofiber scaffolds to control the distribution of drugs. Thanks to recent advancements in medicine and pharmaceuticals, nanofibres may soon be able to transport a wide variety of drugs, allowing for more targeted methods of cellular regeneration and topical medication delivery.
{"title":"Weaving the Future of Topical Medicine: A Journey with Electrospinning Nanofibre Scaffolds","authors":"Ghanshyam Parmar, Jay Mukesh Chudasama, Chintan Aundhia","doi":"10.2174/0115734137311390240630120055","DOIUrl":"https://doi.org/10.2174/0115734137311390240630120055","url":null,"abstract":": The pharmaceutical sciences are gradually shielding mankind from a plethora of deadly but as-of-yet-undiscovered ailments. Many diseases, some of which can be fatal, have their initial line of defence on the skin. A significant challenge for scientists is the development of appropriate pharmacological formulations for transdermal drug administration. Low side effect risk reduces first-pass impact, and good patient compliance makes transdermal distribution superior to oral delivery. This is why transdermal medication delivery is so important. Thanks to advancements in pharmaceutical delivery systems, the skin can now absorb medications more effectively. Researchers from different parts of the globe have investigated many different kinds of medications as possible transdermal delivery routes using electrospinning nanofibres. The skin can more easily absorb therapeutic compounds thanks to the nanofibres' ability to concentrate them. It is possible to load hydrophilic and lipophilic medications onto polymeric nanofibres. Another option is the transdermal distribution of biopolymer nanofibres. Over long periods of time, they control the release of medicinal substances. Nanofibres and nanoparticles allow for the controlled release of both hydrophobic and hydrophilic drugs. Transdermal and topical medication delivery using polymeric electrospinning nanofibres laden with nanoparticles and medicines is the subject of this research review. After that, we'll look at some practical instances of engineers using electrospinning fibres to control the release of drugs in reaction to environmental and internal factors. Afterwards, we will quickly go over the latest developments in tissue engineering, hard tissue engineering [which includes repairing musculoskeletal systems, bones, and cartilage], and cancer therapy that uses electrospin nanofiber scaffolds to control the distribution of drugs. Thanks to recent advancements in medicine and pharmaceuticals, nanofibres may soon be able to transport a wide variety of drugs, allowing for more targeted methods of cellular regeneration and topical medication delivery.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141745101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-18DOI: 10.2174/0115734137294469240702070418
Zirui Liu, Dan Li, Baofeng Zhao, Xifan Mei
Background: Gouty arthritis, characterized by excruciating pain and discomfort, poses a significant burden on patients. While nanomedicines have shown promise in addressing this ailment, their complicated synthesis processes often involve potentially toxic procedures, contributing to adverse side effects in disease management. Methods: In this study, we introduce a straightforward and elegant solution by utilizing easily prepared gold platinum (AuPt) nanoparticles for the treatment of gouty arthritis. The synthesis of these nanoparticles involves the use of gold and platinum precursors in conjunction with NaBH4, simplifying the manufacturing process. Experimental models of gout were established in both in vivo and in vitro settings through lipopolysaccharide and monosodium urate crystal induction. Results: Our findings revealed that AuPt nanoparticles exhibited potent anti-inflammatory effects against gout. This effect was attributed to their ability to activate the Nrf2/HO-1 pathway, resulting in pain alleviation and the inhibition of inflammation, ultimately leading to the reduction of joint edema. With their uncomplicated synthesis and promising therapeutic potential, these simply prepared AuPt nanoparticles emerge as a compelling candidate for pharmaceutical intervention in the treatment of gouty arthritis. Conclusion: This approach not only holds the promise of delivering effective relief to patients but also minimizes the risk of unwanted side effects associated with complex nanomedicine synthesis processes.
{"title":"Therapeutic Effect of Unmodified Gold-platinum Nanoparticles on Gouty Arthritis Via the Nrf2/HO-1 Pathway","authors":"Zirui Liu, Dan Li, Baofeng Zhao, Xifan Mei","doi":"10.2174/0115734137294469240702070418","DOIUrl":"https://doi.org/10.2174/0115734137294469240702070418","url":null,"abstract":"Background: Gouty arthritis, characterized by excruciating pain and discomfort, poses a significant burden on patients. While nanomedicines have shown promise in addressing this ailment, their complicated synthesis processes often involve potentially toxic procedures, contributing to adverse side effects in disease management. Methods: In this study, we introduce a straightforward and elegant solution by utilizing easily prepared gold platinum (AuPt) nanoparticles for the treatment of gouty arthritis. The synthesis of these nanoparticles involves the use of gold and platinum precursors in conjunction with NaBH4, simplifying the manufacturing process. Experimental models of gout were established in both in vivo and in vitro settings through lipopolysaccharide and monosodium urate crystal induction. Results: Our findings revealed that AuPt nanoparticles exhibited potent anti-inflammatory effects against gout. This effect was attributed to their ability to activate the Nrf2/HO-1 pathway, resulting in pain alleviation and the inhibition of inflammation, ultimately leading to the reduction of joint edema. With their uncomplicated synthesis and promising therapeutic potential, these simply prepared AuPt nanoparticles emerge as a compelling candidate for pharmaceutical intervention in the treatment of gouty arthritis. Conclusion: This approach not only holds the promise of delivering effective relief to patients but also minimizes the risk of unwanted side effects associated with complex nanomedicine synthesis processes.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141745099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-11DOI: 10.2174/0115734137294302240625045852
Laila A. Elsayed, Abdullah M. Saif, Shrouk E. Elghol, Maha N. Zayed, Yomna M. Amin, Mohamed H. Omran, Mahmoud A. Ragab, Randa A. Althobiti, Gomaa A.M. Ali
: Cancer, claiming approximately 10 million lives annually, remains a leading cause of global mortality. Conventional cancer treatments, notably chemotherapy and radiotherapy, often entail adverse effects, such as cytotoxicity and the development of resistance, posing significant challenges in cancer management. While natural products have historically served medicinal purposes for various ailments, their recent prominence in combating cancer-related manifestations has surged. Utilizing natural products either alone as antineoplastic agents or in conjunction with conventional chemotherapies presents a promising approach to mitigate these adverse effects. The appeal of natural products lies in their accessibility, versatility, reduced cytotoxic potential, and capacity to counteract drug resistance. Various natural sources offer a diverse range of bioactive compounds capable of influencing various cancer types, modulating signaling pathways, and altering the cancer microenvironment. Notably, many bioactive compounds impact crucial cellular processes like metastasis, angiogenesis, metabolism, proliferation, and viability by targeting specific signaling pathways, particularly those involved in cellular apoptosis. Consequently, the modulation of these factors by natural products significantly affects cancer cell behavior. This comprehensive review explores the application of the promising phytoconstituents as anti-cancer agents across prevalent cancer types, including liver, lung, bladder, breast, leukemia, and colon cancer. In addition, it explores the anti-cancer properties of natural compounds, focusing on their mechanisms and effectiveness against diverse cancers, aiming to improve cancer management.
{"title":"A Comprehensive Review of Promising Phytoconstituents as Anti-Cancer Agents: Biological Mechanisms and Applications Across Different Cancers","authors":"Laila A. Elsayed, Abdullah M. Saif, Shrouk E. Elghol, Maha N. Zayed, Yomna M. Amin, Mohamed H. Omran, Mahmoud A. Ragab, Randa A. Althobiti, Gomaa A.M. Ali","doi":"10.2174/0115734137294302240625045852","DOIUrl":"https://doi.org/10.2174/0115734137294302240625045852","url":null,"abstract":": Cancer, claiming approximately 10 million lives annually, remains a leading cause of global mortality. Conventional cancer treatments, notably chemotherapy and radiotherapy, often entail adverse effects, such as cytotoxicity and the development of resistance, posing significant challenges in cancer management. While natural products have historically served medicinal purposes for various ailments, their recent prominence in combating cancer-related manifestations has surged. Utilizing natural products either alone as antineoplastic agents or in conjunction with conventional chemotherapies presents a promising approach to mitigate these adverse effects. The appeal of natural products lies in their accessibility, versatility, reduced cytotoxic potential, and capacity to counteract drug resistance. Various natural sources offer a diverse range of bioactive compounds capable of influencing various cancer types, modulating signaling pathways, and altering the cancer microenvironment. Notably, many bioactive compounds impact crucial cellular processes like metastasis, angiogenesis, metabolism, proliferation, and viability by targeting specific signaling pathways, particularly those involved in cellular apoptosis. Consequently, the modulation of these factors by natural products significantly affects cancer cell behavior. This comprehensive review explores the application of the promising phytoconstituents as anti-cancer agents across prevalent cancer types, including liver, lung, bladder, breast, leukemia, and colon cancer. In addition, it explores the anti-cancer properties of natural compounds, focusing on their mechanisms and effectiveness against diverse cancers, aiming to improve cancer management.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141613253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Titanium Dioxide (TiO2) is popular in the scientific community due to its wide variety of applications in optoelectronic devices, solar cells, gas sensors, photocatalytic reagents, and the biomedical industry. It is a wide band gap semiconductor with a band gap of 3.2eV. Usually, it shows three different phases, like anatase, rutile, and brookite, based on the synthesis method and annealing temperature. Method: Here, we report a simple chemical process to synthesize TiO2 nanostructures (NSs) at low temperatures to study the impact of growth time on structural and morphological properties. During synthesis, we permitted the samples to grow for 5 hr (sample-T5) and 7 hr (sample-T7) and continued the stirring process accordingly. We performed XRD, UV-Vis, and FESEM analysis with the samples. Result: XRD confirmed the effect of growth time on the size of the structures, and a shift in the absorption edge was observed in UV-Vis spectra, which indicated a change in the band gap. FESEM confirmed the change in nanostructures’ size in both samples. Conclusion: The tuning in band gap due to growth time variation may be an interesting phenomenon to explore for modern scientific applications.
{"title":"Effect of Growth Time on Structural and Optical Properties of Chemically Synthesized TiO2 Nanostructures","authors":"Payal Paul, Dewakar Sharma, Joydeep Biswas, Kamakhya Prakash Misra, Sanjib Kabi, Saikat Chattopadhyay","doi":"10.2174/0115734137306442240630051459","DOIUrl":"https://doi.org/10.2174/0115734137306442240630051459","url":null,"abstract":"Introduction: Titanium Dioxide (TiO2) is popular in the scientific community due to its wide variety of applications in optoelectronic devices, solar cells, gas sensors, photocatalytic reagents, and the biomedical industry. It is a wide band gap semiconductor with a band gap of 3.2eV. Usually, it shows three different phases, like anatase, rutile, and brookite, based on the synthesis method and annealing temperature. Method: Here, we report a simple chemical process to synthesize TiO2 nanostructures (NSs) at low temperatures to study the impact of growth time on structural and morphological properties. During synthesis, we permitted the samples to grow for 5 hr (sample-T5) and 7 hr (sample-T7) and continued the stirring process accordingly. We performed XRD, UV-Vis, and FESEM analysis with the samples. Result: XRD confirmed the effect of growth time on the size of the structures, and a shift in the absorption edge was observed in UV-Vis spectra, which indicated a change in the band gap. FESEM confirmed the change in nanostructures’ size in both samples. Conclusion: The tuning in band gap due to growth time variation may be an interesting phenomenon to explore for modern scientific applications.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141613309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: It has become essential to look into alternatives that effectively stop bacterial infections due to the exponential rise in antibiotic resistance. The field of nanotechnology has made significant strides in development by surmounting obstacles that have impeded success and advancement in other fields. Nanoparticles (NPs) are the key component in the burgeoning field of nanotechnology. Objective: Cyclamen libanoticum leaf extract (CLE) was used as a reducing and capping agent, with silver nitrate (AgNO3) solution as a precursor for synthesizing silver nanoparticles (CLEAgNPs). This study aimed to generate green silver nanoparticles (AgNPs) and assess their antioxidant and antibacterial capacities. Methods: CLE-AgNPs were characterized utilizing UV–vis spectrometry, X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and photoluminescence (PL). Using the radical scavenging assay 2,2-diphenyl-1-picrylhydrazyl (DPPH), the antioxidant activity of CLEAgNPs was evaluated. Several assays were employed to examine the antibacterial effect of CLE-AgNPs against various gram-positive and negative bacteria. Results: Upon analysis, the synthesis revealed 17 nm face-centered cubic CLE-AgNPs (λmax= 431 nm). CLE-AgNPs manifested noticeable antioxidant activity and prominent inhibitory effects on the tested bacteria. The minimum inhibitory concentration (MIC) of the CLE-AgNPs was 31.25 μg/mL for the eight bacterial species. Besides, the results revealed that CLE-AgNPs effectively suppressed the development of bacterial biofilms and could eradicate them. Conclusion: The present investigation introduced Cyclamen libanoticum as a novel bioresource into green chemistry to produce AgNPs with antibacterial and antioxidant capabilities.
{"title":"Cyclamen libanoticum is a Novel Bioresource for Green Silver Nanoparticles with Antibacterial and Antioxidant Capabilities","authors":"Zeinab Hachem, Rayan Kashmar, Alaa Abdallah, Ramadan Awad, Mahmoud Khalil","doi":"10.2174/0115734137310446240616164456","DOIUrl":"https://doi.org/10.2174/0115734137310446240616164456","url":null,"abstract":"Background: It has become essential to look into alternatives that effectively stop bacterial infections due to the exponential rise in antibiotic resistance. The field of nanotechnology has made significant strides in development by surmounting obstacles that have impeded success and advancement in other fields. Nanoparticles (NPs) are the key component in the burgeoning field of nanotechnology. Objective: Cyclamen libanoticum leaf extract (CLE) was used as a reducing and capping agent, with silver nitrate (AgNO3) solution as a precursor for synthesizing silver nanoparticles (CLEAgNPs). This study aimed to generate green silver nanoparticles (AgNPs) and assess their antioxidant and antibacterial capacities. Methods: CLE-AgNPs were characterized utilizing UV–vis spectrometry, X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and photoluminescence (PL). Using the radical scavenging assay 2,2-diphenyl-1-picrylhydrazyl (DPPH), the antioxidant activity of CLEAgNPs was evaluated. Several assays were employed to examine the antibacterial effect of CLE-AgNPs against various gram-positive and negative bacteria. Results: Upon analysis, the synthesis revealed 17 nm face-centered cubic CLE-AgNPs (λmax= 431 nm). CLE-AgNPs manifested noticeable antioxidant activity and prominent inhibitory effects on the tested bacteria. The minimum inhibitory concentration (MIC) of the CLE-AgNPs was 31.25 μg/mL for the eight bacterial species. Besides, the results revealed that CLE-AgNPs effectively suppressed the development of bacterial biofilms and could eradicate them. Conclusion: The present investigation introduced Cyclamen libanoticum as a novel bioresource into green chemistry to produce AgNPs with antibacterial and antioxidant capabilities.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141587102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.2174/0115734137319139240614103935
Li Meng, Jidong Zhang, Cheng Chen, Shihao Dai, Qiong Li, Kun Xiang
Introduction: The development of cost-effective and efficient catalysts plays a pivotal role in the realization of hydrogen production through electrochemical water splitting. Method: In this study, two-dimensional NiCo2S4 nanosheets weresynthesized usinga hydrothermal method followed by a sulfidation process. Results: The resulting materials were thoroughly characterized to understand their morphology and structure. The findings indicate that the NiCo2S4 nanosheets exhibit exceptional electrical conductivity and a high density of pores, which facilitate electrolyte infiltration and interfacial charge transfer during electrochemical reactions. Furthermore, the incorporation of S2− modulates the electronic structure of metal ions, reducing the oxidation potential of metal sites and promoting the surface reconstruction of the electrode to form active species. Electrochemical tests conducted in a 1 M KOH solution using the synthesized catalyst as the working electrode demonstrate an overpotential of merely 280 mV and 300 mV at a current density of 20 mA cm−2 and 40 mA cm−2 , respectively, which are much lower than those of NiCo-LDH electrodes (360 mV and 410 mV). Conclusion: Furthermore, the NiCo2S4 electrode delivers a remarkably low Tafel slope of 47.9 mV dec−1 . This investigation presents a novel approach to the development of efficient transition metal-based electrocatalysts.
{"title":"Two-Dimensional NiCo2S4 Nanosheets Deliver Efficient Oxygen Evolution Reaction","authors":"Li Meng, Jidong Zhang, Cheng Chen, Shihao Dai, Qiong Li, Kun Xiang","doi":"10.2174/0115734137319139240614103935","DOIUrl":"https://doi.org/10.2174/0115734137319139240614103935","url":null,"abstract":"Introduction: The development of cost-effective and efficient catalysts plays a pivotal role in the realization of hydrogen production through electrochemical water splitting. Method: In this study, two-dimensional NiCo2S4 nanosheets weresynthesized usinga hydrothermal method followed by a sulfidation process. Results: The resulting materials were thoroughly characterized to understand their morphology and structure. The findings indicate that the NiCo2S4 nanosheets exhibit exceptional electrical conductivity and a high density of pores, which facilitate electrolyte infiltration and interfacial charge transfer during electrochemical reactions. Furthermore, the incorporation of S2− modulates the electronic structure of metal ions, reducing the oxidation potential of metal sites and promoting the surface reconstruction of the electrode to form active species. Electrochemical tests conducted in a 1 M KOH solution using the synthesized catalyst as the working electrode demonstrate an overpotential of merely 280 mV and 300 mV at a current density of 20 mA cm−2 and 40 mA cm−2 , respectively, which are much lower than those of NiCo-LDH electrodes (360 mV and 410 mV). Conclusion: Furthermore, the NiCo2S4 electrode delivers a remarkably low Tafel slope of 47.9 mV dec−1 . This investigation presents a novel approach to the development of efficient transition metal-based electrocatalysts.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141587103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.2174/0115734137296780240529172003
Shaojun Wu, Xianglai Xu
: Carbon nanotube films are utilized in various fields, particularly electric heating, owing to their exceptional thermal and electrical properties. However, quantitative research on the electrothermal characteristics of carbon nanotube film is insufficient, and glass fiberreinforced epoxy-resin composites prepared through the electrothermal method of carbon nanotube films (i.e., the out-of-autoclave technique) have not yet been reported. Herein, according to a mathematical model and experimental demonstration, a quantitative relationship, T = T0 + (t/L2)·(V2σ)·(1/αw), was proposed to explain the electrothermal properties of carbon nanotube films. Glass fiber-reinforced composites with an outstanding tensile strength of 535.6 MPa and an elongation-at-break of 1.6% were prepared through the out-of-autoclave technique using the designed carbon nanotube film. The composites outperformed previous mechanical composites in terms of energy consumption. Experimental investigations and molecular simulations revealed the mechanical mechanisms of the composites. These findings quantitatively revealed the electrothermal properties of carbon nanotube films, advancing their application in the out-ofautoclave manufacturing of high-performance resin-matrix composites.
:碳纳米管薄膜因其优异的热学和电学特性被广泛应用于各个领域，尤其是电加热领域。然而，有关碳纳米管薄膜电热特性的定量研究尚不充分，通过碳纳米管薄膜电热法（即釜外技术）制备玻璃纤维增强环氧树脂复合材料的研究也尚未见报道。本文根据数学模型和实验证明，提出了一个定量关系 T = T0 + (t/L2)-(V2σ)-(1/αw) 来解释碳纳米管薄膜的电热特性。利用所设计的碳纳米管薄膜，通过釜外技术制备了玻璃纤维增强复合材料，其拉伸强度达到 535.6 兆帕，断裂伸长率为 1.6%。该复合材料在能耗方面优于以往的机械复合材料。实验研究和分子模拟揭示了复合材料的机械机理。这些发现定量揭示了碳纳米管薄膜的电热特性，推动了其在高压釜外制造高性能树脂基复合材料中的应用。
{"title":"Quantitative Study on the Electrothermal Properties of Carbon Nanotube Film and its Out-of-Autoclave-Manufactured Glass Fiber-Reinforced Epoxy-Resin Composites","authors":"Shaojun Wu, Xianglai Xu","doi":"10.2174/0115734137296780240529172003","DOIUrl":"https://doi.org/10.2174/0115734137296780240529172003","url":null,"abstract":": Carbon nanotube films are utilized in various fields, particularly electric heating, owing to their exceptional thermal and electrical properties. However, quantitative research on the electrothermal characteristics of carbon nanotube film is insufficient, and glass fiberreinforced epoxy-resin composites prepared through the electrothermal method of carbon nanotube films (i.e., the out-of-autoclave technique) have not yet been reported. Herein, according to a mathematical model and experimental demonstration, a quantitative relationship, T = T0 + (t/L2)·(V2σ)·(1/αw), was proposed to explain the electrothermal properties of carbon nanotube films. Glass fiber-reinforced composites with an outstanding tensile strength of 535.6 MPa and an elongation-at-break of 1.6% were prepared through the out-of-autoclave technique using the designed carbon nanotube film. The composites outperformed previous mechanical composites in terms of energy consumption. Experimental investigations and molecular simulations revealed the mechanical mechanisms of the composites. These findings quantitatively revealed the electrothermal properties of carbon nanotube films, advancing their application in the out-ofautoclave manufacturing of high-performance resin-matrix composites.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141587104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Rice husk is an important agricultural waste that contains organic mass and bio-silica. Although some rice husks have been used as fuel, animal food, filler for wine fermentation, and fertilizer, the majority are discarded as agricultural waste, which does great harm to the environment. The conversion of rice husk to silicon carbide (SiC)-based materials satisfies the demand for the reutilization of solid wastes. Methods: The article reviews recent progress and patents on the SiC-based materials from rice husk. The possible development directions of the SiC-based materials from rice husks are also analyzed. Results: SiC materials with different morphologies, including microscale and nanoscale particles, nanoscale whiskers, and nanowires, can be prepared by high-temperature carbothermal reduction reaction from rice husk at the temperature of 1200-1800 °C, reaction time of 0.5-8 h, respectively. SiC-based composites, including SiC nanowires/C, Al/SiC, SiC/Si3N4, and SiC/Al2O3, can be obtained using rice husk as main source materials at 800-1800 °C. SiC-based materials exhibit great application potential in the fields of absorbents, optical devices, mechanical products, photocatalysts, semiconductors, and Li-ion batteries. Conclusion: The low cost of preparing SiC-based materials from rice husk, combining them with different compositions, and exploring new applications are important research directions in the future.
背景：稻壳是一种重要的农业废弃物，含有有机质和生物硅。虽然有些稻壳被用作燃料、动物食品、葡萄酒发酵的填充物和肥料，但大部分稻壳都作为农业废弃物被丢弃，对环境造成了极大的危害。将稻壳转化为碳化硅（SiC）基材料，满足了固体废弃物再利用的需求。方法：文章回顾了稻壳制碳化硅基材料的最新进展和专利。还分析了稻壳碳化硅基材料可能的发展方向。结果：在温度为 1200-1800 ℃、反应时间为 0.5-8 h 的条件下，利用稻壳的高温碳热还原反应可以制备出不同形貌的 SiC 材料，包括微米级和纳米级颗粒、纳米级晶须和纳米线。以稻壳为主要原料，在 800-1800 ℃下可制备出 SiC 基复合材料，包括 SiC 纳米线/C、Al/SiC、SiC/Si3N4 和 SiC/Al2O3。SiC 基材料在吸附剂、光学器件、机械产品、光催化剂、半导体和锂离子电池等领域具有巨大的应用潜力。结论从稻壳中低成本制备 SiC 基材料，并将其与不同成分相结合，探索新的应用领域，是未来的重要研究方向。
{"title":"Silicon Carbide-based Materials from Rice Husk","authors":"Qianmin Cong, Xingxing Zhu, Zhangjie Ban, Junzhe Li, Zhengyu Cai, Lizhai Pei","doi":"10.2174/0115734137316974240620095136","DOIUrl":"https://doi.org/10.2174/0115734137316974240620095136","url":null,"abstract":"Background: Rice husk is an important agricultural waste that contains organic mass and bio-silica. Although some rice husks have been used as fuel, animal food, filler for wine fermentation, and fertilizer, the majority are discarded as agricultural waste, which does great harm to the environment. The conversion of rice husk to silicon carbide (SiC)-based materials satisfies the demand for the reutilization of solid wastes. Methods: The article reviews recent progress and patents on the SiC-based materials from rice husk. The possible development directions of the SiC-based materials from rice husks are also analyzed. Results: SiC materials with different morphologies, including microscale and nanoscale particles, nanoscale whiskers, and nanowires, can be prepared by high-temperature carbothermal reduction reaction from rice husk at the temperature of 1200-1800 °C, reaction time of 0.5-8 h, respectively. SiC-based composites, including SiC nanowires/C, Al/SiC, SiC/Si3N4, and SiC/Al2O3, can be obtained using rice husk as main source materials at 800-1800 °C. SiC-based materials exhibit great application potential in the fields of absorbents, optical devices, mechanical products, photocatalysts, semiconductors, and Li-ion batteries. Conclusion: The low cost of preparing SiC-based materials from rice husk, combining them with different compositions, and exploring new applications are important research directions in the future.","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141587106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-06DOI: 10.2174/0115734137294889240314032718
H. Bhardwaj, Sulekha Khute, Ram Kumar Sahu, R. Jangde
Polymers are supermolecules or huge molecules that have a central role as an excipient in any dosage formulation. Currently, the usage of polymers in drug formulation is often associated with numerous problems connected with drug release, side effects, and carcinogenic effects. Therefore, the utilization of water-soluble polymers and polymeric nanoparticles has been favoured to minimize these types of problems. Polymers can be found in natural and synthetic resources and they are manipulated according to their chemical and biological activity in cells and tissues. Their major advantages include improving therapeutic efficacy, reduced toxicity, loading capacity, drug release rate, greater efficacy, targeted delivery, prolonged circulation time, and physical and chemical stability. Thus, this review focuses on the classifications of polymers such as HPMC, HEC, CMC, PVP, Pectin, chitosan, alginate polyacetylene, polythiophene, polypyrrole, polyphenylene, polyaniline, etc., the needs and drawbacks of herbal polymers, factors affecting biodegradation polymers, key properties of water-soluble polymers as well as their properties. This review also deals with various commercial biopolymers and the associated challenges. The properties of polymeric nanoparticles (PNP) as drug carriers and their diverse applications are discussed. PNPs such as polymeric micelles, niosome, dendrimers, liposomes and colloidal carriers composed of biodegradable polymers are widely used drug carriers. PNPs are produced to decrease toxicity, improve therapeutic efficacy, and increase drug permeation due to good compatibility with lipophilic and oil-soluble drugs. The performance of polymers is an important factor in current biomedical and pharmaceutical applications. Furthermore, the formulation of PNP focuses on improving applications in nanotechnology.
{"title":"Recent Advances in Water-Soluble Polymer and Polymeric Nanoparticles\u0000for Pharmaceutical Application","authors":"H. Bhardwaj, Sulekha Khute, Ram Kumar Sahu, R. Jangde","doi":"10.2174/0115734137294889240314032718","DOIUrl":"https://doi.org/10.2174/0115734137294889240314032718","url":null,"abstract":"\u0000\u0000Polymers are supermolecules or huge molecules that have a central role as an excipient\u0000in any dosage formulation. Currently, the usage of polymers in drug formulation is often\u0000associated with numerous problems connected with drug release, side effects, and carcinogenic\u0000effects. Therefore, the utilization of water-soluble polymers and polymeric nanoparticles has\u0000been favoured to minimize these types of problems. Polymers can be found in natural and synthetic\u0000resources and they are manipulated according to their chemical and biological activity in\u0000cells and tissues. Their major advantages include improving therapeutic efficacy, reduced toxicity,\u0000loading capacity, drug release rate, greater efficacy, targeted delivery, prolonged circulation\u0000time, and physical and chemical stability. Thus, this review focuses on the classifications of\u0000polymers such as HPMC, HEC, CMC, PVP, Pectin, chitosan, alginate polyacetylene, polythiophene,\u0000polypyrrole, polyphenylene, polyaniline, etc., the needs and drawbacks of herbal polymers,\u0000factors affecting biodegradation polymers, key properties of water-soluble polymers as\u0000well as their properties. This review also deals with various commercial biopolymers and the\u0000associated challenges. The properties of polymeric nanoparticles (PNP) as drug carriers and their\u0000diverse applications are discussed. PNPs such as polymeric micelles, niosome, dendrimers, liposomes\u0000and colloidal carriers composed of biodegradable polymers are widely used drug carriers.\u0000PNPs are produced to decrease toxicity, improve therapeutic efficacy, and increase drug permeation\u0000due to good compatibility with lipophilic and oil-soluble drugs. The performance of polymers\u0000is an important factor in current biomedical and pharmaceutical applications. Furthermore,\u0000the formulation of PNP focuses on improving applications in nanotechnology.\u0000","PeriodicalId":10827,"journal":{"name":"Current Nanoscience","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141380136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：