Pelayo Leon-Jimenez, Maria Lorenzo-Martin, Cristiana Tomatis-Souverbielle, Shoghik Akoghlanian, Linda Cripe, Octavio Ramilo, Asuncion Mejias
{"title":"Pan-valvulitis in Children with Kawasaki Disease: A Case Report and Review of the Literature.","authors":"Pelayo Leon-Jimenez, Maria Lorenzo-Martin, Cristiana Tomatis-Souverbielle, Shoghik Akoghlanian, Linda Cripe, Octavio Ramilo, Asuncion Mejias","doi":"10.1097/inf.0000000000004203","DOIUrl":null,"url":null,"abstract":"We present a rare case of pan-valvular involvement in a 5-month-old female with Kawasaki disease shock syndrome despite early treatment with intravenous immunoglobulin and corticosteroids. She experienced a favorable outcome after the addition of infliximab, which was guided based on clinical, laboratory and echocardiogram findings, rather than recrudescence of fever, the most common indicator of intravenous immunoglobulin resistance.","PeriodicalId":501652,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":"61 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Pediatric Infectious Disease Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/inf.0000000000004203","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
We present a rare case of pan-valvular involvement in a 5-month-old female with Kawasaki disease shock syndrome despite early treatment with intravenous immunoglobulin and corticosteroids. She experienced a favorable outcome after the addition of infliximab, which was guided based on clinical, laboratory and echocardiogram findings, rather than recrudescence of fever, the most common indicator of intravenous immunoglobulin resistance.
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