Executive Functioning, Internalizing and Externalizing Symptoms: Understanding Developmental Dynamics Through Panel Network Approaches

JAACAP open Pub Date : 2024-03-01 Epub Date: 2023-12-04 DOI:10.1016/j.jaacop.2023.11.001
René Freichel MSc , Janine Pfirrmann MSc , Peter J. de Jong PhD , Janna Cousijn PhD , Ingmar H.A. Franken PhD , Albertine J. Oldehinkel PhD , Ilya M. Veer PhD , Reinout W. Wiers PhD
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Abstract

Objective

Early adolescence is a transition period during which many mental health disorders emerge. The interplay between different internalizing and externalizing mental health problems in adolescence is poorly understood at the within-person level. Executive functioning (EF) in early adolescence has been shown to constitute a transdiagnostic risk factor, but the specificity of the associations between different domains of EF and mental health problems remains unclear.

Method

Network dynamics (ie, temporal effects) of different internalizing and externalizing symptoms were investigated leveraging data from the Tracking Adolescents’ Individual Lives Survey (TRAILS), a large longitudinal panel study of adolescents (>1,641 participants) assessed at ages 11, 13, and 15. Two novel methodological panel network approaches were used: cross-lagged panel network models and graphical vector autoregressive models. Hierarchical regression models were used to investigate prospective associations between different measures of EF and broadband transdiagnostic dimensions.

Results

Depressive problems predicted a range of other internalizing symptoms (ie, panic, somatic problems, separation anxiety, general anxiety, social phobia) over time, particularly during early adolescence. Important feedback loops with reciprocal associations between different anxiety symptoms were identified. Different facets of EF assessed at age 11, particularly sustained attention, showed weak but significant prospective associations with internalizing and externalizing symptoms at age 13.

Conclusion

The present findings emphasize the importance of targeting depressive problems in early adolescence to prevent a spiral of different internalizing symptoms from arising later on.

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执行功能、内化症状和外化症状--通过小组网络方法了解发展动态
目标青春早期是一个过渡时期,在此期间会出现许多心理健康障碍。人们对青春期各种内化和外化心理健康问题之间的相互作用知之甚少。研究利用了追踪青少年个人生活调查(TRAILS)的数据,对不同内化和外化症状的网络动力学(即时间效应)进行了调查。TRAILS是一项大型纵向小组研究,对11、13和15岁的青少年(1641名参与者)进行了评估。研究采用了两种新颖的面板网络方法:交叉滞后面板网络模型和图形向量自回归模型。结果随着时间的推移,特别是在青春期早期,抑郁问题会预测一系列其他内化症状(即恐慌、躯体问题、分离焦虑、一般焦虑、社交恐惧症)。研究发现了不同焦虑症状之间相互关联的重要反馈回路。结论:本研究结果强调了在青春期早期针对抑郁问题进行治疗的重要性,以防止日后不同的内化症状螺旋式上升。
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JAACAP open
JAACAP open Psychiatry and Mental Health
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