Mechanism of Action of Many Drugs Depend on Enzyme Inhibition

R. Ayyad, A. Nejm, Yasser Abdel Allem Hassan, Ahmed R. Ayyad
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Abstract

Enzyme inhibition is an important process in the mode of action of many drugs used in the treatment of various diseases. Antibiotics, anti-hypertensive agents, anti-hyperlipidaemic, anti-glaucoma, and anti-malarial drugs act on specific enzymes, leading to bacteriostatic or bactericidal effects, lower blood pressure, reduce cholesterol levels, and cause smooth muscle relaxation of blood vessels. Understanding the mode of action of these drugs and how they affect enzymes is crucial for the development of new drugs and the optimization of existing therapies. This article highlights some various drugs that act through enzyme inhibition and their mechanisms of action.
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许多药物的作用机制取决于酶抑制作用
酶抑制是治疗各种疾病的许多药物作用方式中的一个重要过程。抗生素、降压药、抗高脂血药、抗青光眼和抗疟疾药物作用于特定的酶,产生抑菌或杀菌作用,降低血压,降低胆固醇水平,使血管平滑肌松弛。了解这些药物的作用模式以及它们如何影响酶对于开发新药和优化现有疗法至关重要。本文重点介绍了几种通过酶抑制作用的药物及其作用机制。
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