3D modeling of the airflow and aerosol deposition in the existence of dust

IF 0.7 4区 材料科学 Q3 Materials Science Materials Express Pub Date : 2023-12-01 DOI:10.1166/mex.2023.2563
O. Altwijri, Razan Bakhshwin, E. H. Mirza, Y. A. Algabri, S. Chatpun, Ravish Javed
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Abstract

Annually, more than two million deaths are caused due to the exposure of air pollution which cause damage to the lungs and the respiratory system. Topography, light-textured topsoil, drought, and desert climate make Saudi Arabia vulnerable to sand storms and dust. The study aims to examine the deposition of dust particles in the human airway and its relationship to asthma and investigate the possibility that the dust deposition would be changed with different particle size diameters. An idealized upper respiratory tract 3D model was constructed with computer-aided design software. Later a computational simulation was performed using computational fluid dynamics with 3 different sizes (0.03, 2, and 9 microns) of the dust particles to find out the change in airflow velocity and pressure. Our findings revealed that small size particles will travel more with less inertia, whereas bigger size particles will travel less but with higher inertia at airflow rates of 30 L/min. It was found that dust deposition in the respiratory system determines the probability of inhalation and total deposition in the alveoli greatly varies with particle diameter size. An idealized URT model replicate patient-specific URT geometry which helped in finding real-time airflow velocity and pressure of dust particles. Particles with smaller diameter are capable of 100% deposition and inhalation rate at the alveoli, whereas particles with bigger diameter tend to deposit less and with lower inhalation rates at the alveoli.
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气流和气溶胶沉积在尘埃中的三维模型
每年有200多万人因接触空气污染而死亡,空气污染对肺部和呼吸系统造成损害。地形、轻质表土、干旱和沙漠气候使沙特阿拉伯容易受到沙尘暴和沙尘的影响。本研究旨在探讨人体气道中粉尘颗粒的沉积及其与哮喘的关系,并探讨不同粒径粉尘颗粒沉积变化的可能性。利用计算机辅助设计软件建立理想的上呼吸道三维模型。然后用计算流体力学方法对3种不同尺寸(0.03、2、9微米)的粉尘颗粒进行了计算模拟,得到了气流速度和压力的变化情况。我们的研究结果表明,当气流速率为30 L/min时,小颗粒在惯性较小的情况下运动得更多,而大颗粒在惯性较大的情况下运动得更少。研究发现,呼吸系统的粉尘沉积决定了吸入的概率,肺泡内的粉尘沉积总量随颗粒物直径的大小变化很大。理想的URT模型复制了患者特定的URT几何形状,有助于发现实时气流速度和粉尘颗粒的压力。直径较小的颗粒在肺泡的沉积和吸入速率可达100%,而直径较大的颗粒在肺泡的沉积和吸入速率往往较少。
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来源期刊
Materials Express
Materials Express NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY
自引率
0.00%
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69
审稿时长
>12 weeks
期刊介绍: Information not localized
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