Virtual screening and identification of promising therapeutic compounds against drug-resistant Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein synthase I (KasA)
Alexander M. Andrianov, Konstantin V. Furs, Anna V. Gonchar, Alena M. Skrahina, Yixin Wang, Liang-Dong Lyu, Alexander V. Tuzikov
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Abstract
The emergence of new Mycobacterium tuberculosis (Mtb) strains resistant to the key drugs currently used in the clinic for tuberculosis treatment can substantially reduce the probability of therapy ...