Monoterpenes as potential antifungal molecules against Candida cell membranes: in-vitro and in-silico studies

Nafis Raj, Khalid Umar Fakhri, Prerna Pathak, Saiema Ahmedi, Nikhat Manzoor
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Abstract

Azoles are the frequently used antifungal drugs that target the enzyme lanosterol 14 α-demethylase (erg11p). This enzyme plays a vital role in ergosterol biosynthesis and hence maintainenance of ce...
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单萜作为抗念珠菌细胞膜的潜在抗真菌分子:体外和体内研究
唑类是常用的抗真菌药物,以羊毛甾醇 14 α-脱甲基酶(erg11p)为靶标。这种酶在麦角甾醇的生物合成过程中起着重要作用,因此也是维持真菌生长的关键因素。
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