Synthesis, molecular modelling and pharmacological evaluation of novel indole-thiazolidinedione based hybrid analogues as potential pancreatic lipase inhibitors

Ginson George, Prashant S. Auti, Pracheta Sengupta, Nisha Yadav, Atish T. Paul
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Abstract

A series of novel indole-thiazolidinedione hybrid analogues (7a to 7 u) were synthesised, characterised and evaluated for their potential Pancreatic Lipase (PL) inhibition. Amongst the screened ana...
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作为潜在胰脂肪酶抑制剂的新型吲哚-噻唑烷二酮混合类似物的合成、分子建模和药理学评价
研究人员合成了一系列新型吲哚-噻唑烷二酮杂化类似物(7a 至 7 u),并对其潜在的胰脂肪酶(PL)抑制作用进行了表征和评估。在筛选出的类似物中...
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