Structure-based molecular docking and molecular dynamics simulations study for the identification of dipeptidyl peptidase 4 inhibitors in type 2 diabetes

Xi Chen, Bin Xue, Shadma Wahab, Armiya Sultan, Mohammad Khalid, Song Yang
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Abstract

Inhibition of dipeptidyl peptidase-4 (DPP4) activity has emerged as a promising therapeutic approach for the treatment of type 2 diabetes mellitus (T2DM). Bioinformatics-driven approaches have emer...
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基于结构的分子对接和分子动力学模拟研究,鉴定 2 型糖尿病二肽基肽酶 4 抑制剂
抑制二肽基肽酶-4(DPP4)的活性已成为治疗2型糖尿病(T2DM)的一种很有前景的治疗方法。生物信息学驱动的方法已经出现。
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