Determination of N-nitroso folic acid in folic acid and multivitamin supplements by LC-MS/MS

Yun Zeng, Jessie Teo, Jing-Quan Lim, Wei-Kiat Hoi, Chee-Leong Kee, Min-Yong Low, Xiaowei Ge
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Abstract

Analysis of N-nitroso folic acid, a nitrosamine impurity found in folic acid, is challenging due to the complex sample matrices. Many of such supplements contain not only a variety of vitamins, inc...
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利用 LC-MS/MS 法测定叶酸和多种维生素补充剂中的 N-亚硝基叶酸
由于样品基质复杂,分析叶酸中的亚硝胺杂质 N-亚硝基叶酸具有挑战性。许多此类营养补充剂不仅含有多种维生素,还含有多种微量元素。
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