The analgesic efficacy of pectoral nerve block for breast augmentation: a meta-analysis of randomized controlled studies.

IF 1 4区医学 Q3 ORTHOPEDICS Journal of Plastic Surgery and Hand Surgery Pub Date : 2023-12-14 DOI:10.2340/jphs.v58.9395

Hailin Yang, Hao Wang, Qi Wang

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Abstract

Background: Many patients suffered from serious pain after breast augmentation, but the analgesic efficacy of pectoral nerve block for these patients was not well established. Thus, this meta-analysis was intended to study the analgesic efficacy of pectoral nerve block for breast augmentation.

Methods: Several databases including PubMed, EMbase, Web of Science, EBSCO, and Cochrane library databases were searched, and we included randomized controlled trials (RCTs) regarding the analgesic efficacy of pectoral nerve block for breast augmentation.

Results: Six RCTs were ultimately included in this meta-analysis. Compared with control intervention for breast augmentation, pectoral nerve block could significantly reduce pain scores at 1 h (mean difference [MD] = -2.28; 95% confidence interval [CI] = -3.71 to -0.85; P = 0.002), 2 h (MD = -3.08; 95% CI = -3.95 to -2.20; P < 0.00001), 4 h (MD = -2.95; 95% CI = -3.32 to -2.58; P < 0.00001), 6-8 h (MD = -2.68; 95% CI = -3.24 to -2.11; P < 0.00001), 24 h (MD = -2.04; 95% CI = -2.41 to -1.67; P < 0.00001), the number of analgesic requirement (odd ratio [OR] = 0.20; 95% CI = 0.09 to 0.45; P = 0.0001), and the incidence of nausea (OR = 0.21; 95% CI = 0.08 to 0.54; P = 0.001) and vomiting (OR = 0.15; 95% CI = 0.05 to 0.39; P = 0.0001). Conclusions: Pectoral nerve block may be effective for pain relief after breast augmentation.

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胸神经阻滞对隆胸术的镇痛效果：随机对照研究的荟萃分析。

背景：许多患者在隆胸术后遭受严重的疼痛，但胸神经阻滞对这些患者的镇痛效果尚未得到很好的证实。因此，本荟萃分析旨在研究胸神经阻滞对隆胸术的镇痛效果：方法：我们检索了多个数据库，包括 PubMed、EMbase、Web of Science、EBSCO 和 Cochrane 图书馆数据库，并纳入了有关胸神经阻滞对隆胸术镇痛效果的随机对照试验（RCT）：本荟萃分析最终纳入了六项随机对照试验。与隆胸对照干预相比，胸神经阻滞可显著降低1 h（平均差 [MD] = -2.28；95% 置信区间 [CI] = -3.71 to -0.85；P = 0.002）、2 h（MD = -3.08；95% CI = -3.95 to -2.20；P < 0.00001）、4 h（MD = -2.95；95% CI = -3.32 to -2.58；P < 0.00001）、6-8 h（MD = -2.68; 95% CI = -3.24 to -2.11; P < 0.00001）、24 h（MD = -2.04; 95% CI = -2.41 to -1.67; P < 0.00001）、镇痛剂需求次数（奇数比 [OR] = 0.20; 95% CI = 0.09 to 0.45; P = 0.0001），以及恶心（OR = 0.21; 95% CI = 0.08 to 0.54; P = 0.001）和呕吐（OR = 0.15; 95% CI = 0.05 to 0.39; P = 0.0001）的发生率。结论胸大肌神经阻滞可有效缓解隆胸术后的疼痛。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Plastic Surgery and Hand Surgery ORTHOPEDICS-SURGERY

CiteScore

2.10

自引率

0.00%

发文量

108

审稿时长

6-12 weeks

期刊介绍： The purpose of the Journal of Plastic Surgery and Hand Surgery is to serve as an international forum for plastic surgery, hand surgery and related research. Interest is focused on original articles on basic research and clinical evaluation. The scope of the journal comprises: • Articles concerning operative methods and follow-up studies • Research articles on subjects related to plastic and hand surgery • Articles on cranio-maxillofacial surgery, including cleft lip and palate surgery. Extended issues are published occasionally, dealing with special topics such as microvascular surgery, craniofacial surgery, or burns. Supplements, usually doctoral theses, may also be published. The journal is published for the Acta Chirurgica Scandinavica society and sponsored by the Key Foundation, Sweden. The journal was previously published as Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery.