Effects of Race and Gender Classifications on Atherosclerotic Cardiovascular Disease Risk Estimates for Clinical Decision-Making in a Cohort of Black Transgender Women.

IF 2.6 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Health Equity Pub Date : 2023-11-30 eCollection Date: 2023-01-01 DOI:10.1089/heq.2023.0066

Tonia Poteat, Elle Lett, Ashleigh J Rich, Huijun Jiang, Andrea L Wirtz, Asa Radix, Sari L Reisner, Alexander B Harris, Jowanna Malone, William G La Cava, Catherine R Lesko, Kenneth H Mayer, Carl G Streed

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Abstract

Introduction: Despite their dynamic, socially constructed, and imprecise nature, both race and gender are included in common risk calculators used for clinical decision-making about statin therapy for atherosclerotic cardiovascular disease (ASCVD) prevention.

Methods and materials: We assessed the effect of manipulating six different race-gender categories on ASCVD risk scores among 90 Black transgender women.

Results: Risk scores varied by operationalization of race and gender and affected the proportion for whom statins were recommended.

Discussion: Race and gender are social constructs underpinning racialized and gendered health inequities. Their rote use in ASCVD risk calculators may reinforce and perpetuate existing inequities.

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黑人变性女性队列中种族和性别分类对用于临床决策的动脉粥样硬化性心血管疾病风险估计值的影响。

导言：尽管种族和性别具有动态、社会建构和不精确的性质，但它们都被纳入了常用的风险计算器中，用于预防动脉粥样硬化性心血管疾病（ASCVD）的他汀类药物治疗的临床决策：我们评估了操作六个不同种族-性别类别对 90 名黑人变性女性 ASCVD 风险评分的影响：结果：风险评分因种族和性别的操作而异，并影响推荐使用他汀类药物的比例：讨论：种族和性别是社会建构，是种族化和性别化健康不平等的基础。在 ASCVD 风险计算器中生搬硬套地使用种族和性别可能会强化和延续现有的不平等。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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