A test of competing mediators linking trouble sleeping to cannabis use in adolescents and emerging adults.

IF 2.4 3区 医学 Q3 PHARMACOLOGY & PHARMACY Experimental and clinical psychopharmacology Pub Date : 2024-06-01 Epub Date: 2023-12-21 DOI:10.1037/pha0000693
Benjamin L Berey, Samuel Meisel, Melissa Pielech, Jamie E Parnes, Hayley Treloar Padovano, Robert Miranda
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Abstract

This study examined day-level associations between trouble sleeping and three cannabis-use indices (likelihood/quantity of use and impaired control). We evaluated behavioral and cognitive mediators of the association between trouble sleeping and cannabis outcomes. Youth (N = 86, ages 15-24, 48.8% female, 58.8% White, 18.6% Latine) who regularly used cannabis were recruited for an intervention study. This preregistered secondary data analysis leveraged data from a 1-week ecological momentary assessment (EMA) study completed prior to intervention. Trouble sleeping, cannabis use, and impaired control over use were assessed each morning; negative affect, risk-taking propensity, and cannabis craving were assessed multiple times and aggregated to create a daily average. Multilevel structural equation modeling evaluated hypothesized temporally sequenced associations and putative mechanisms at the day (i.e., within) and person (i.e., between) level. In bivariate analyses at the person level, there were large-effect associations between trouble sleeping and craving and negative affect, and between craving and cannabis-use likelihood and quantity (rs from .34 to .48). In multilevel analyses at the day level, participants were less likely to use cannabis the next day after reporting more trouble sleeping (β = -.65, p < .001). Trouble sleeping was not directly associated with subsequent cannabis-use quantity or impaired control, or indirectly via negative affect, risk-taking propensity, or craving. Trouble sleeping had differential relations with cannabis-use indices at the day and person levels. To promote youth health and reduce cannabis use, future research may consider the unique, person- and situation-driven mechanistic processes at play. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

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测试青少年和新成人中睡眠障碍与吸食大麻之间的竞争中介关系。
本研究考察了睡眠障碍与三个大麻使用指数(使用可能性/数量和控制能力受损)之间的日水平关联。我们还评估了睡眠障碍与大麻使用结果之间的行为和认知调节因素。我们招募了经常使用大麻的青少年(N = 86,15-24 岁,48.8% 为女性,58.8% 为白人,18.6% 为拉丁裔)进行干预研究。这项预先登记的二次数据分析利用了干预前完成的为期一周的生态瞬间评估(EMA)研究数据。每天早上对睡眠障碍、大麻使用和使用控制能力受损进行评估;对负面情绪、冒险倾向和大麻渴求进行多次评估,并汇总得出日平均值。多层次结构方程模型评估了假设的时间序列关联以及日(即日内)和人(即人与人之间)层面的推定机制。在个人层面的二元分析中,失眠与渴求和负面情绪之间,以及渴求与吸食大麻的可能性和数量之间,都存在大效应关联(rs 从 0.34 到 0.48 不等)。在按天进行的多层次分析中,参与者在报告失眠次数增多后,第二天使用大麻的可能性较低(β = -.65,p < .001)。失眠与随后的大麻使用量或控制能力受损没有直接关系,也没有通过消极情绪、冒险倾向或渴求间接相关。在日和人的层面上,失眠与大麻使用指数的关系各不相同。为了促进青少年健康和减少大麻使用,未来的研究可能会考虑到独特的、由个人和情况驱动的机制过程。(PsycInfo Database Record (c) 2023 APA,保留所有权利)。
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来源期刊
CiteScore
4.20
自引率
8.70%
发文量
164
审稿时长
6-12 weeks
期刊介绍: Experimental and Clinical Psychopharmacology publishes advances in translational and interdisciplinary research on psychopharmacology, broadly defined, and/or substance abuse.
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