Marco Zaffanello, Erika Bonacci, Giorgio Piacentini, Luana Nosetti, Emilio Pedrotti
{"title":"Pediatric Ocular Health and Obstructive Sleep Apnea Syndrome: A Review.","authors":"Marco Zaffanello, Erika Bonacci, Giorgio Piacentini, Luana Nosetti, Emilio Pedrotti","doi":"10.3390/pediatric15040066","DOIUrl":null,"url":null,"abstract":"<p><p>Obstructive sleep apnea (OSA) affects neurobehavioral, cognitive, and cardiovascular aspects, particularly in children, by obstructing the upper airways during sleep. While its impact in adult ocular health is recognized, there is ongoing debate about OSA's relevance in pediatrics. This review explores the relationship between OSA and ocular health in children, focusing on the effects and potential improvements through treatment. A systematic search found 287 articles through PubMeD/MEDLINE, Scopus, Web of Science, and ScienceDirect; 94.4% were excluded. After careful selection, six English articles were included, addressing the effects of OSA on children's eyes. Three studies examined choroidal alterations, three explored retinal and optic nerve changes, and two analyzed ocular changes following otorhinolaryngological intervention. The immediate correlation in children is inconclusive, but age may be a contributing factor. Pediatric OSA patients exhibit corneal anomalies and increased optic nerve thickness, possibly due to intermittent hypoxia. OSA influences retinal vascular density in children, with increased density after treatment and reduced choroidal thickness in cases of adenotonsillar hypertrophy. This review emphasized OSA's significant impact on children's ocular health, revealing alterations in the optic nerve, choroid, retina, and cornea. While the direct correlation with the optic nerve is not always evident, OSA raises intraocular pressure and induces structural changes. Treatment holds promise, highlighting the need for regular monitoring to promptly address childhood OSA.</p>","PeriodicalId":45251,"journal":{"name":"Pediatric Reports","volume":"15 4","pages":"741-749"},"PeriodicalIF":1.4000,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10747302/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/pediatric15040066","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Obstructive sleep apnea (OSA) affects neurobehavioral, cognitive, and cardiovascular aspects, particularly in children, by obstructing the upper airways during sleep. While its impact in adult ocular health is recognized, there is ongoing debate about OSA's relevance in pediatrics. This review explores the relationship between OSA and ocular health in children, focusing on the effects and potential improvements through treatment. A systematic search found 287 articles through PubMeD/MEDLINE, Scopus, Web of Science, and ScienceDirect; 94.4% were excluded. After careful selection, six English articles were included, addressing the effects of OSA on children's eyes. Three studies examined choroidal alterations, three explored retinal and optic nerve changes, and two analyzed ocular changes following otorhinolaryngological intervention. The immediate correlation in children is inconclusive, but age may be a contributing factor. Pediatric OSA patients exhibit corneal anomalies and increased optic nerve thickness, possibly due to intermittent hypoxia. OSA influences retinal vascular density in children, with increased density after treatment and reduced choroidal thickness in cases of adenotonsillar hypertrophy. This review emphasized OSA's significant impact on children's ocular health, revealing alterations in the optic nerve, choroid, retina, and cornea. While the direct correlation with the optic nerve is not always evident, OSA raises intraocular pressure and induces structural changes. Treatment holds promise, highlighting the need for regular monitoring to promptly address childhood OSA.
阻塞性睡眠呼吸暂停(OSA)会在睡眠过程中阻塞上呼吸道,从而影响神经行为、认知和心血管等方面,尤其是对儿童而言。虽然人们已经认识到 OSA 对成人眼部健康的影响,但关于 OSA 与儿科的相关性仍存在争议。这篇综述探讨了 OSA 与儿童眼部健康之间的关系,重点关注其影响以及通过治疗可能带来的改善。通过PubMeD/MEDLINE、Scopus、Web of Science和ScienceDirect进行系统检索,共发现287篇文章,其中94.4%的文章被排除在外。经过仔细筛选,共收录了六篇英文文章,内容涉及 OSA 对儿童眼睛的影响。其中三篇研究探讨了脉络膜的变化,三篇探讨了视网膜和视神经的变化,两篇分析了耳鼻喉科干预后眼部的变化。儿童的直接相关性尚无定论,但年龄可能是一个因素。小儿 OSA 患者表现出角膜异常和视神经厚度增加,这可能是由于间歇性缺氧所致。OSA 影响儿童视网膜血管密度,治疗后密度增加,腺样体肥大病例脉络膜厚度减少。这篇综述强调了 OSA 对儿童眼部健康的重大影响,揭示了视神经、脉络膜、视网膜和角膜的改变。虽然与视神经的直接关联并不总是很明显,但 OSA 会升高眼压并诱发结构变化。治疗是有希望的,因此需要定期监测,及时解决儿童 OSA 问题。