Chocolate toxicosis in pets

Nicole Bates
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Abstract

Chocolate ingestion is very common in pets, particularly dogs, but has also been reported in other animals including cats and rabbits. Most cases occur around Christmas and Easter, when large amounts of chocolate are often present in the home in the form of chocolate bars, snacks, confectionery, Easter eggs and chocolate figurines. Chocolate-covered raisins, nuts and coffee beans present an additional toxicological hazard in dogs. The type of chocolate is defined in law by the percentage of cocoa solids, with dark (plain) chocolate containing more than milk chocolate. The main toxic component of chocolate is theobromine, a methylxanthine, although caffeine, another methylxanthine, is also present. These cause central nervous system stimulation with cardiac and respiratory hyperactivity. Signs include gastrointestinal effects, excitability, hyperactivity, tachycardia, tremors, hypertension and hyperthermia. Signs of toxicosis generally occur within a few hours of ingestion. The mainstays of treatment are decontamination and supportive care with rehydration, control of central nervous system stimulation and arrhythmias as required. Most pets recover fully, and death is uncommon; however, prognosis is more guarded in pets with seizures or arrhythmias.
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宠物巧克力中毒症
宠物(尤其是狗)摄入巧克力的情况非常普遍,但也有其他动物(包括猫和兔子)摄入巧克力的报道。大多数病例发生在圣诞节和复活节前后,因为这段时间家里经常会有大量巧克力,如巧克力棒、零食、糖果、复活节彩蛋和巧克力塑像等。裹有巧克力的葡萄干、坚果和咖啡豆对狗的毒性危害更大。巧克力的种类在法律上是根据可可固形物的百分比来定义的,黑巧克力(纯巧克力)的含量高于牛奶巧克力。巧克力的主要有毒成分是可可碱(一种甲基黄嘌呤),但也含有咖啡因(另一种甲基黄嘌呤)。这些成分会刺激中枢神经系统,引起心脏和呼吸亢进。症状包括胃肠道反应、兴奋、多动、心动过速、震颤、高血压和高热。中毒症状一般在摄入后数小时内出现。治疗的主要方法是净化和支持性护理,必要时补液、控制中枢神经系统刺激和心律失常。大多数宠物都能完全康复,死亡的情况并不常见;但是,对于癫痫发作或心律失常的宠物来说,预后就比较危险了。
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