Effect of blood glucose & glycated hemoglobin levels on the outcome of patients with acute exacerbation of chronic obstructive pulmonary disease

JV Praveen, K. Preethi, B. Padmaja
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Abstract

The connection to hyperglycaemia & intense intensifications of persistent obstructive pneumonic infection (COPD) are presently starting to arise. Expanded blood glucose is related with unfriendly clinical results among patients with significant ailments. Hyperglycemia might be related with expanded mortality, length of stay (LOS), & re-confirmations in COPD patients. This study was finished in 80 hospitalized patients with intense compounding of persistent obstructive aspiratory sickness in the Department of pneumonic medication between June 2021 to January 2022. The segment, clinical data, lab results, radiographic outcomes, & data on Length of stay (LOS), mortality & re-confirmation were gathered. Point of the review is to concentrate on the impact of blood glucose, HbA1c levels on the mean length of medical clinic stay in patients of AECOPD. Out of 80 COPD individuals, 61(76%) were male & 19(24%) were female. Majority belonged to 56-65 years (38.8%), followed by 66-75 years (28.8%). Of the total 80 COPD individuals, 100% of male patients (n=61) were smokers, 15% of females (n=3) were smokers. Duration of the hospital stay was more with higher RBS values of ≥200mg/dl (9.2 ± 3.5 days) when compared to RBS value of 171-200 mg/dl (7.6±2.3 days) which was more than the RBS group with values of 141-170 (7.2±1.9 days). Whereas for normal RBS values of ≤140 mg/dl mean duration of hospital stay was (5.12±0.82 days). The conclusion arrived from our study, Higher the RBS at the time of admission, longer the mean duration of stay in the hospital. At admission, RBS more than 170 mg/dl is detrimental in AECOPD patients. High HbA1C levels (>6%) were associated with a high risk of exacerbations.
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血糖和糖化血红蛋白水平对慢性阻塞性肺病急性加重患者预后的影响
目前,高血糖与顽固性阻塞性肺部感染(COPD)的剧烈恶化之间的联系开始出现。血糖升高与重大疾病患者的不良临床结果有关。高血糖可能与慢性阻塞性肺病患者死亡率、住院时间(LOS)和再次确诊率的增加有关。这项研究是在 2021 年 6 月至 2022 年 1 月期间,对肺部药物治疗部 80 名住院的持续性阻塞性呼吸道疾病重症患者进行的。研究收集了患者的病程、临床数据、实验室结果、影像学结果以及住院时间(LOS)、死亡率和再次确诊的数据。审查的重点是血糖和 HbA1c 水平对 AECOPD 患者平均住院时间的影响。在 80 名慢性阻塞性肺病患者中,61(76%)人为男性,19(24%)人为女性。大多数患者年龄在 56-65 岁之间(38.8%),其次是 66-75 岁(28.8%)。在总共 80 名慢性阻塞性肺病患者中,100% 的男性患者(61 人)是吸烟者,15% 的女性患者(3 人)是吸烟者。与 RBS 值为 171-200 mg/dl 组(7.6±2.3 天)相比,RBS 值≥200mg/dl 组(9.2±3.5 天)的住院时间长于 RBS 值为 141-170 组(7.2±1.9 天)。而正常 RBS 值≤140 mg/dl 组的平均住院时间为(5.12±0.82 天)。我们的研究得出的结论是,入院时 RBS 越高,平均住院时间越长。入院时 RBS 超过 170 mg/dl 对 AECOPD 患者不利。高 HbA1C 水平(>6%)与病情加重的高风险相关。
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