Invasive solid papillary carcinoma of breast mimicking as a benign condition: Rare case report

Krishna Ramavath, G. Singh L., Reshmi Sultana, Sumitra Sivakoti, Adarsha A M, Harikrishna B, Siddharth S Rao
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Abstract

Invasive papillary carcinomas of breast are rare tumors. They account for approximately 0.5% of all Invasive breast carcinomas. Invasive papillary carcinomas are commonly present in post-menopause women. These tumors lack the myoepithelial cell layer (MCL) within the papillae or at the periphery of the tumor. The diagnosis is difficult due to different clinical and radiological features. Immunohistochemistry (IHC) is really essential to confirming the diagnosis. We are here presenting one index case of a rare variety of invasive papillary carcinoma of the left breast. We present a case of invasive papillary carcinoma of the left breast in a 55-year-old female presented with a retroareolar lump without nipple discharge. Preoperative core biopsy showed fibroadenoma with a papillary configuration.But post-operative histopathological examination revealed it was an invasive papillary carcinoma. Invasive papillary carcinoma of breast even though a rare entity, making a diagnosis is very challenging. Thorough preoperative clinical and radiological examination should be done, so that timely management as well as proper treatment is possible.
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乳腺浸润性实性乳头状癌疑似良性病变罕见病例报告
乳腺浸润性乳头状癌是一种罕见肿瘤。它们约占所有浸润性乳腺癌的 0.5%。浸润性乳头状癌常见于绝经后妇女。这些肿瘤在乳头内或肿瘤外围缺乏肌上皮细胞层(MCL)。由于临床和放射学特征各不相同,诊断十分困难。免疫组织化学(IHC)对确诊至关重要。我们在此介绍一例罕见的左乳腺浸润性乳头状癌病例。我们报告了一例左乳腺浸润性乳头状癌病例,患者是一名 55 岁女性,因乳晕后肿块就诊,无乳头溢液。术前核心活检显示为乳头状结构的纤维腺瘤,但术后组织病理学检查显示为浸润性乳头状癌。乳腺浸润性乳头状癌虽然罕见,但诊断却非常困难。术前应进行全面的临床和放射学检查,以便及时处理和正确治疗。
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