Prevalence of thrombocytopenia among Indian patients who are on chemotherapeutic drugs in five cities of India: A cross sectional descriptive study

M. Verma, Parmila Malik, Jyotsana Khattri, Veeresh Vg, A. Khajuria, Lalit Singh
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Abstract

Chemotherapeutic drugs are chemical drugs used in management of cancer, these drugs are chemotoxic and has varied number of adverse effects. Thrombocytopenia is one such adverse effect, thrombocytopenia is the condition in which the platelets counts are less than few lakhs and cause the symptoms of the bleeding. The present study desiged to find the prevalence of thrombocytopenia among Indians who are on chemotherapeutic drugs.: a descriptive cross section survey design used to identify the prevalence rate of thrombocytopenia among patients who are on chemotherapeutic drugs in India the cities studied are Lucknow 268 patients, Panipath 357 patients, Sonipath 384 patients, Gohana 291 patients, Delhi 445 patients, a total 1745 patients were under chemotherapeutic drugs of which 281 patients developed thrombocytopenia, in the samples collected analyzed at various selected diagnostic centers.: The present study found that in Lucknow for 268 patients on chemotherapy 37 patients samples developed thrombocytopenia, Panipath for 357 patients on chemotherapy 76 patients samples developed thrombocytopenia, Sonipath for 384 patients on chemotherapy 68 patients samples developed thrombocytopenia, Gohana for 291 patients on chemotherapy 32 patients samples developed thrombocytopenia and in Delhi for 445 patients on chemotherapy 68 patients samples developed thrombocytopenia respectively. The overall prevalence of thrombocytopenia among patients who are on chemotherapeutic drugs is 16.01%. chemo drugs are vital in management of cancer conditions, these drugs are best currently known in reducing or killing the cancer cells, however they also carry a bag of adverse effects which hampers the wellbeing of patients hence, the knowledge and prevalence rate of thrombocytopenia in patients under chemotherapy plays a vital role in primordial prevention and better management of thrombocytopenia in its occurrence.
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印度五个城市服用化疗药物的印度患者中血小板减少症的发病率:横断面描述性研究
化疗药物是用于治疗癌症的化学药物,这些药物具有化学毒性,会产生多种不良反应。血小板减少症就是其中一种不良反应,血小板减少症是指血小板计数低于数十万,并导致出血症状的情况。本研究旨在了解服用化疗药物的印度人中血小板减少症的发病率。研究城市包括勒克瑙(Lucknow)268 名患者、帕尼帕斯(Panipath)357 名患者、索尼帕斯(Sonipath)384 名患者、戈哈纳(Gohana)291 名患者和德里(Delhi)445 名患者:本研究发现,在勒克瑙,268 名化疗患者中有 37 个样本出现血小板减少症;在 Panipath,357 名化疗患者中有 76 个样本出现血小板减少症;在 Sonipath,384 名化疗患者中有 68 个样本出现血小板减少症;在 Gohana,291 名化疗患者中有 32 个样本出现血小板减少症;在德里,445 名化疗患者中有 68 个样本出现血小板减少症。化疗药物在癌症治疗中至关重要,这些药物是目前已知的减少或杀死癌细胞的最佳药物,但它们也会带来一系列不良反应,影响患者的健康,因此,了解化疗患者血小板减少的知识和患病率对于初步预防和更好地管理血小板减少症的发生至关重要。
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