Overview of the epidemic characteristics of Mycoplasma pneumoniae infection around COVID pandemic

iLABMED Pub Date : 2023-12-18 DOI:10.1002/ila2.27
Hongmei Sun, Li Xiao
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Abstract

Mycoplasma pneumoniae (M. pneumoniae) is a cell wall-less respiratory pathogen causing community-acquired pneumonia and extrapulmonary manifestations. It is transmitted through close contact and shows periodic regional outbreaks. The coronavirus disease (COVID-19) pandemic interfered with the global spread of M. pneumoniae. A large-scale post-COVID outbreak is currently ongoing in China. To help physicians better understand and manage this epidemic, we provide this review summarizing current knowledge on the pathogenesis, epidemic characteristics, macrolide resistance, diagnostic methods, and clinical treatment strategies for this pathogen.

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COVID 大流行前后肺炎支原体感染的流行特征概述
肺炎支原体(M. pneumoniae)是一种无细胞壁的呼吸道病原体,可引起社区获得性肺炎和肺外表现。它通过密切接触传播,并呈周期性区域性爆发。冠状病毒病(COVID-19)大流行干扰了肺炎双球菌的全球传播。目前,中国正在大规模爆发后冠状病毒病。为了帮助医生更好地了解和管理这一疫情,我们在本综述中总结了目前有关该病原体的发病机制、流行特点、大环内酯类耐药性、诊断方法和临床治疗策略等方面的知识。
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