{"title":"Review finds little benefit from higher-than-recommended doses of stimulants","authors":"","doi":"10.1002/pu.31117","DOIUrl":null,"url":null,"abstract":"<p>A systematic review and meta-analysis of studies involving adults with attention-deficit hyperactivity disorder (ADHD) has found small or no benefit from stimulant doses that exceed levels recommended in regulatory guidelines. Unlicensed doses of methylphenidate or amphetamines also were found to increase risk of treatment dropout due to adverse events. Results of the systematic review and meta-analysis were published online Oct. 25, 2023, in <i>JAMA Psychiatry.</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31117","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A systematic review and meta-analysis of studies involving adults with attention-deficit hyperactivity disorder (ADHD) has found small or no benefit from stimulant doses that exceed levels recommended in regulatory guidelines. Unlicensed doses of methylphenidate or amphetamines also were found to increase risk of treatment dropout due to adverse events. Results of the systematic review and meta-analysis were published online Oct. 25, 2023, in JAMA Psychiatry..