Distribution of group a Rotavirus circulating in Mashhad, Iran.

IF 1.3 Q4 MICROBIOLOGY Iranian Journal of Microbiology Pub Date : 2023-12-01 DOI:10.18502/ijm.v15i6.14160

Kiana Ketabi, Zahra Meshkat, Hoorieh Soleimanjahi, Ali Teimoori, Hamid Tanzadepanah, Faezeh Bakhshi

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Abstract

Background and objectives: Group A Rotavirus (RVA) is the most important causative agent of acute diarrheal disease in pediatrics 5 years and below. This study aimed to determine the distribution of circulating RVA in Mashhad, Iran to develop health improvement strategies and vaccine decision making.

Materials and methods: A total of 106 fecal specimens were collected from children admitted to Akbar and Dr. Sheikh referral pediatric hospitals of Mashhad City during the December 2020 to March 2021 and December 2021 to March 2022. All specimens were tested for specific bacterial, parasitic, and amoebic infections. Negative samples were analyzed for RVA infections using the RT-PCR method.

Results: RVA was detected in 31.3% of the specimens, indicating no statistical significance in gender distribution or between fall and winter positivity rates. The number of RVA-positive specimens increased following age increasing in the range of 1 to 60 months.

Conclusion: Today, acute diarrheal disease (ADD) is still caused mostly by Rotavirus infections in pediatrics in Mashhad. Comprehensive studies are needed to determine the genetic diversity of circulating Rotavirus strains in this era.

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伊朗马什哈德流行的 a 组轮状病毒的分布情况。

背景和目的：A 组轮状病毒（RVA）是 5 岁及以下儿童急性腹泻病的最主要病原体。本研究旨在确定 RVA 在伊朗马什哈德的分布情况，以制定健康改善策略和疫苗决策：在 2020 年 12 月至 2021 年 3 月和 2021 年 12 月至 2022 年 3 月期间，从马什哈德市 Akbar 和 Sheikh 医生儿科转诊医院住院的儿童中收集了 106 份粪便标本。对所有样本进行了特定细菌、寄生虫和阿米巴感染检测。采用 RT-PCR 方法对阴性样本进行 RVA 感染分析：31.3%的样本中检测到了 RVA，表明性别分布或秋冬季阳性率之间没有统计学意义。随着年龄在 1 到 60 个月之间的增长，RVA 阳性标本的数量也在增加：如今，在马什哈德的儿科中，急性腹泻病（ADD）仍主要由轮状病毒感染引起。需要进行全面研究，以确定当前流行的轮状病毒毒株的遗传多样性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Microbiology MICROBIOLOGY-

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.