THYROID CANCER INCIDENCE IN THE POPULATION OF UKRAINE AND ITS EPIDEMIOLOGICAL DETERMINANTS: IONIZING RADIATION AND ENDOCRINE DISRUPTORS.

A Ye Prysyazhnyuk, D A Bazyka, N A Gudzenko, M M Fuzik, N G Babkina, O M Khukhrianska, S A Danevych
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Abstract

Objective: to estimate the risk of thyroid cancer incidence in the population of Ukraine in connection with its exposure to radioactive iodine fallout of Chornobyl origin and the use of pesticides in agricultural production in the country.

Object of study: Incidence rates of thyroid cancer in the population of Ukraine in 2001-2019, average regional radiation doses absorbed by the thyroid because of the Chornobyl accident, the volume of use of various groups of pesticides in the regions of Ukraine.

Research methods: statistical, mathematical and cartographic.

Results: The study covering the period of 2001-2019, revealed significant temporal and regional differences in the thyroid cancer incidence in the population of the Ukraine regions in 2001-2019. The existence of a significant correlation between the thyroid cancer incidence and the amount of radiation exposure to the thyroid associated with the Chornobyl accident was established. The existence of a significant correlation between the thyroid cancer incidence and the degree of pesticide use intensity in agriculture in the Ukraine regions was established. A significant value of multiple correlation r = 0.5866 (p < 0.05) was found between the thyroid cancer incidence in Ukraine andthe average regional radiation doses and the pesticide use intensity in agricultural production in the country.

Conclusions: A reliable value of the multiple correlation between the value of the average regional radiation exposure doses to the thyroid associated with the Chornobyl accident and the degree of pesticide use intensity in the national economy of Ukraine and the thyroid cancer incidence in the population was determined.

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乌克兰人口的甲状腺癌发病率及其流行病学决定因素:电离辐射和内分泌干扰物。
目的:估算乌克兰人口甲状腺癌发病风险与接触切尔诺贝利放射性碘沉降物和在农业生产中使用杀虫剂的关系:2001-2019年乌克兰人口甲状腺癌发病率、切尔诺贝利事故造成的甲状腺吸收的地区平均辐射剂量、乌克兰各地区各类杀虫剂的使用量:研究覆盖 2001-2019 年,发现 2001-2019 年乌克兰各地区人口甲状腺癌发病率存在显著的时间和地区差异。甲状腺癌发病率与切尔诺贝利核电站事故导致的甲状腺辐射量之间存在明显的相关性。甲状腺癌发病率与乌克兰各地区农业中农药使用强度之间存在明显的相关性。乌克兰甲状腺癌发病率与地区平均辐射剂量和农业生产中农药使用强度之间的多重相关性r = 0.5866 (p < 0.05):切尔诺贝利事故对甲状腺造成的地区平均辐射剂量值、乌克兰国民经济中农药使用强度与人口甲状腺癌发病率之间存在可靠的多重相关性。
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Problemy radiatsiinoi medytsyny ta radiobiolohii
Problemy radiatsiinoi medytsyny ta radiobiolohii Medicine-Radiology, Nuclear Medicine and Imaging
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