[Behavioral Variant of Frontotemporal Dementia: A Case Report of a 54-Year-Old Female Patient].

Q3 Pharmacology, Toxicology and Pharmaceutics Neuropsychopharmacologia Hungarica Pub Date : 2023-12-01
Eliza Polyak
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Abstract

Frontotemporal dementia is a neurodegenerative disease characterized by atrophy of the frontal and temporal lobes of the brain, and it is believed to primarily develop based on genetic factors. Its initial symptoms can appear relatively early, even between the ages of 40-50, affecting approximately 15-22 individuals out of 100,000 annually. The disease manifests in various forms, categorized into behavioral, aphasic, and motor variants due to its diverse presentations. The behavioral variant, constituting about half of the cases, is the most common type. It involves personality changes, behavioral problems, and cognitive decline, with patients surviving an average of 8.5 years from the onset of symptoms. Currently, there is no curative therapy available, and only symptomatic treatment can be administered to improve the quality of life. In the case we presented, the symptoms of the behavioral variant of frontotemporal dementia appeared atypically, accompanied by perceptual disturbances and a paranoid attitude, further complicating the definitive diagnosis.

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[额颞叶痴呆的行为变异:一名 54 岁女性患者的病例报告]。
额颞叶痴呆症是一种以大脑额叶和颞叶萎缩为特征的神经退行性疾病,据信其发病主要与遗传因素有关。它的初期症状可以出现得比较早,甚至在 40-50 岁之间就会出现,每年每 10 万人中大约有 15-22 人患病。该病的表现形式多种多样,由于其表现的多样性,可分为行为变异型、失语型和运动变异型。行为变异型约占病例的一半,是最常见的类型。它包括人格改变、行为问题和认知能力下降,患者从症状出现起平均存活 8.5 年。目前还没有治疗方法,只能通过对症治疗来改善生活质量。在我们介绍的病例中,额颞叶痴呆的行为变异症状出现得并不典型,还伴有知觉障碍和偏执态度,这使得明确诊断变得更加复杂。
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来源期刊
Neuropsychopharmacologia Hungarica
Neuropsychopharmacologia Hungarica Medicine-Medicine (all)
CiteScore
1.60
自引率
0.00%
发文量
8
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