Combination treatment of a deep diabetic toe ulcer with collagenase-santyl dressings and antibiotics: A case report

Salkapuram Sunil Kumar , Karthikeyan Elumalai , Srinivasan Sivannan , Sivaneswari Srinivasan , Santhana Krishnan Ramanujam , Binoy Varghese Cherian
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Abstract

A diabetic foot ulcer is defined as the ulceration of tissues brought on by trauma and some peripheral neurological abnormalities, primarily as a result of the bacterial infection. The infection of the toe's surrounding tissue is the primary cause of the infectious diabetic toe ulcer. In this case report, a 58-year-old male patient with a deep foot ulcer was admitted to the emergency ward on October 15, 2022, due to pus discharge at the right big toe of the foot. Antibiotics like Vancomycin 30mg per kg twice per day and Ciprofloxacin 400mg twice per day were suggested, along with enzymatic debridement therapy, which helps stop infections faster. A decrease in wound size and an improvement in overall health showed that the patient's response to the combination therapy was encouraging. The use of collagenase-santyl dressings, along with suitable antibiotics, can play a crucial role in the successful treatment of foot ulcers by facilitating wound healing and preventing complications like cellulitis or osteomyelitis.

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用胶原酶-山奈敷料和抗生素联合治疗深层糖尿病足趾溃疡:病例报告
糖尿病足溃疡是指由外伤和一些周围神经异常引起的组织溃疡,主要是细菌感染的结果。脚趾周围组织的感染是感染性糖尿病足趾溃疡的主要原因。在本病例报告中,一名 58 岁的足部深溃疡男性患者于 2022 年 10 月 15 日因右脚大脚趾处有脓性分泌物而被送入急诊病房。医生建议使用抗生素,如万古霉素每公斤 30 毫克,每天两次;环丙沙星 400 毫克,每天两次;同时使用酶法清创疗法,这有助于更快地阻止感染。伤口面积的缩小和总体健康状况的改善表明,患者对综合疗法的反应令人鼓舞。使用胶原酶山奈敷料和适当的抗生素,可以促进伤口愈合,预防蜂窝组织炎或骨髓炎等并发症,从而在成功治疗足部溃疡方面发挥关键作用。
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