Mind-body techniques on stress-induced gut microbiota dysbiosis in Asthmatics: A narrative review

Abstract

Asthma is more common when a particular type of pathogenic gut microbiota is present, whereas the presence of some beneficial bacteria lowers the frequency of asthma attacks. Cortisol levels rise when the HPA axis is activated by stress. The diversity of the gut microbiota and the permeability of the digestive system may be interfered with by an activated HPA axis. Additionally, stress affects peripheral mononuclear cell activity, lymphocyte proliferation, natural killer cell activity, and IgA antibody levels. Intestinal microbial dysbiosis and leaky gut can be caused by low IgA concentration, low polymorphonuclear cell count, and active NK cells, and lymphocytes. Asthma is brought on by intestinal microbiota dysbiosis and bacterial translocation, which are associated with low-grade inflammation. Mind-body medicine is an alternative form of therapy, including yoga, and mindfulness practices. For instance, Qigong meditation has also been shown to reduce HPA axis activity, improve immune function, and reduce asthma symptoms. Pro-inflammatory cytokines including IL-6, IL-7, and TNF-alpha have been shown to decrease with the use of mind-body medicine techniques. In order to prevent microbial translocation, yoga can boost IgA, CD4 + cells, and NK cell concentrations. Mind-body medicine can reduce CRH and cortisol levels as well as stop microbial dysbiosis. In this review, we want to emphasize how these practices reduce stress, inhibit the activation of the HPA axis, prevent gut microbial dysbiosis, encourage the proliferation of antiasthmatic bacteria, and decrease the diversity of pathogenic, and opportunistic asthmatic bacteria.