Severity of COVID-19 Pneumonia in Kidney Transplant Recipients According to SARS-CoV-2 Vaccination.

IF 2.8 Q2 INFECTIOUS DISEASES Infection and Chemotherapy Pub Date : 2023-12-01 DOI:10.3947/ic.2023.0083
Seunghyeok Choi, Hanbi Lee, Sang Hun Eum, Ji-Won Min, Hye Eun Yoon, Chul Woo Yang, Byung Ha Chung
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Abstract

We reviewed 24 kidney transplantat recipients (KTRs) who had radiologically confirmed coronavirus disease 2019 (COVID-19) pneumonia. Enrolled KTRs were divided into a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-vaccination (+) group (n = 18) and a vaccination (-) group (n = 6). Clinical outcomes of the two groups including death, pulmonary outcome, and renal outcome were compared. COVID-19 pneumonia was worse in vaccination (-) KTRs. Two out of six vaccination (-) KTRs needed continuous renal replacement therapy (CRRT) and mechanical ventilator (MV) and expired. In contrast, only one KTR expired and required CRRT and MV out of 18 vaccination (+) KTRs. Our results suggest that SARS-CoV-2 vaccination attenuates severity of COVID-19 pneumonia in KTRs.

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肾移植受者 COVID-19 肺炎的严重程度与 SARS-CoV-2 疫苗接种有关。
我们对 24 例经放射学证实患有 2019 年冠状病毒病(COVID-19)肺炎的肾移植受者(KTR)进行了回顾性研究。入组的 KTR 被分为严重急性呼吸系统综合征冠状病毒 2 (SARS-CoV-2) 疫苗接种 (+) 组(18 人)和疫苗接种 (-) 组(6 人)。比较了两组的临床结果,包括死亡、肺部结果和肾脏结果。接种疫苗(-)的 KTR 患 COVID-19 肺炎的情况更严重。六名接种疫苗(-)的 KTR 中,有两人需要持续肾脏替代疗法 (CRRT) 和机械呼吸机 (MV),并最终死亡。相比之下,在 18 例接种疫苗(+)的 KTR 中,只有 1 例 KTR 死亡并需要接受 CRRT 和 MV 治疗。我们的研究结果表明,接种 SARS-CoV-2 疫苗可减轻 KTR 患者 COVID-19 肺炎的严重程度。
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来源期刊
Infection and Chemotherapy
Infection and Chemotherapy INFECTIOUS DISEASES-
CiteScore
6.60
自引率
11.90%
发文量
71
审稿时长
22 weeks
期刊最新文献
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